Outbound | Return | Airlines | Shop | Baggage | Price | ||
---|---|---|---|---|---|---|---|
Best option San Francisco Santo Domingo | Outbound 04/29/25 1 Stopover (FLL) B60378, B62549 10h 28min | Return 05/08/25 1 Stopover (JFK) B62510, B60115 15h 56min | | ![]() | ? | $513 | |
San Francisco Santo Domingo | Outbound 09/19/25 4 Stopovers (MSP, DTW, FLL, MCO) SY0396, NK2383, NK3721, NK0196, NK1567 28h 52min | Return 09/29/25 3 Stopovers (MIA, DTW, MSP) DM2100, NK0292, NK2388, SY0393 28h 43min | | ![]() | $554 | ||
San Francisco Santo Domingo | Outbound 09/19/25 1 Stopover (PTY) CM0383, CM0298 32h 42min | Return 09/29/25 1 Stopover (PTY) CM0299, CM0382 12h 31min | | ![]() | ? | $541 | |
San Francisco Santo Domingo | Outbound 09/19/25 1 Stopover (JFK) B60816, B61009 11h 52min | Return 09/29/25 1 Stopover (BOS) B61930, B60733 13h 34min | | ![]() | ? | $544 | |
San Francisco Santo Domingo | Outbound 04/29/25 1 Stopover (MIA) AA0369, DM2105 11h 06min | Return 05/08/25 1 Stopover (JFK) B62510, B60115 15h 56min | | ![]() | ? | $555 | |
San Francisco Santo Domingo | Outbound 04/29/25 3 Stopovers (LAS, JFK, EWR, SJU) F92486, F93238, F93573, F90097 27h 45min | Return 05/08/25 2 Stopovers (SJU, ATL) F90096, F92871, F91949 17h 22min | | ![]() | ? | $583 | |
San Francisco Santo Domingo | Outbound 07/25/25 2 Stopovers (PHX, MIA) AA2414, AA3044, AA1856 21h 00min | Return 08/17/25 1 Stopover (MIA) AA1856, AA2426 13h 56min | | ![]() | ? | $639 | |
San Francisco Santo Domingo | Outbound 09/19/25 2 Stopovers (SEA, MIA) AS0922, AS0305, DM2105 21h 56min | Return 09/29/25 2 Stopovers (MIA, SEA) DM2100, AS0305, AS1166 27h 13min | | ![]() | ? | $642 | |
San Francisco Santo Domingo | Outbound 09/19/25 1 Stopover (PTY) CM0383, CM0298 32h 42min | Return 09/29/25 1 Stopover (PTY) CM0299, CM0382 12h 31min | | ![]() | ? | $643 | |
San Francisco Santo Domingo | Outbound 09/19/25 1 Stopover (MIA) AA2753, AA2171 22h 06min | Return 09/29/25 2 Stopovers (MIA, LAX) AA2171, AA0669, AA3247 18h 57min | | ![]() | ? | $661 |
Airline
- American Airlines
- Copa Airlines
- JetBlue Airways
- Alaska Airlines
- Frontier Airlines
Tips and tricks to help you find cheap flights from San Francisco to Santo Domingo
Favorite airline: e.g. Aeroméxico, Avianca
Aeroméxico is the most popular airline for flights from San Francisco to Santo Domingo.

Aeroméxico
36 %

Avianca
36 %

Copa
27 %
Favourite connection: via Panama City
The most popular route is via Panama City and is booked by 50 % of all travelers.
Route
bookings
1 stopover Panama City-Tocumen International
20h 22min, from $551
50 %
2 stopovers San Salvador Guatemala City
13h 05min, from $525
33 %
2 stopovers Guadalajara Mexico City-Juarez International
13h 39min, from $586
17 %
Important flight information
Flight information: San Francisco - Santo Domingo
Roundtrip from | $512.14 |
---|---|
Distance | 5520 km |
Departure airport | Airport San Francisco International Airport, CA (SFO) |
Arrival airport | Airport Santo Domingo, Dominican Republic (SDQ) |
Destination country | Flights to Dominican Republic |
Alternative routes to Dominican Republic
- Flight San Francisco - Punta Cana from $460
Alternative flights to Santo Domingo
- Flight Boston - Santo Domingo from $359
- Flight Fort Lauderdale - Santo Domingo from $259
- Flight Orlando - Santo Domingo from $305
- Flight Baltimore - Santo Domingo from $296
- Flight Newark - Santo Domingo from $311
- Flight Philadelphia - Santo Domingo from $360
- Flight New York - Santo Domingo from $240
- Flight Los Angeles - Santo Domingo from $442
- Flight Charlotte - Santo Domingo from $284
- Flight Miami - Santo Domingo from $210
Flight destinations with a similar price
- Flight Santo Domingo - Frankfurt from $1,080
Flight destinations with a similar price
- Flight San Francisco - Hilo from $497
- Flight San Francisco - Brussels from $513
- Flight San Francisco - Zurich from $542
- Flight San Francisco - Havana from $526
- Flight San Francisco - Munich from $556
- Flight San Francisco - Saigon from $561
- Flight San Francisco - Barcelona from $509
- Flight San Francisco - Madrid from $523
- Flight San Francisco - Paris from $550