- Cheapest roundtrip flight
- from€563
- Fastest flight
- non-stop flights
- 30x / week
- Flight distance
- 1,478 km
- Time difference
- Most popular airlines
- Copa Airlines
- Copa Airlines
Flight schedule from Santo Domingo (SDQ) to Panama City (PTY)
Select a travel date in the flight schedule for the route from Santo Domingo (SDQ) to Panama City (PTY) and compare affordable flight deals.
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- Aug 30 – Sep 5, 2026
- September 6 – 12, 2026
- September 13 – 19, 2026
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Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Santo Domingo to Panama City?
A nonstop flight from Santo Domingo to Panama City typically takes around 2 hours 35 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 16 hours 5 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.
Are there nonstop flights from Santo Domingo to Panama City?
Yes, there are nonstop flights from Santo Domingo to Panama City, averaging around 4 to 5 flights per day, operated by, among others, Copa. If you want to fly without a layover, it is worth filtering specifically for nonstop flights when searching.
Which airlines fly from Santo Domingo to Panama City?
Direct flights from Santo Domingo to Panama City are operated by, among others, Copa. Connecting flights with one stop are also available, for example with Avianca (via Bogota). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.
On which days are there nonstop flights from Santo Domingo to Panama City?
Nonstop flights from Santo Domingo to Panama City operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Santo Domingo to Panama City?
On the route from Santo Domingo to Panama City, there are on average around 4 to 5 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.
How many flights per week are there from Santo Domingo to Panama City?
From Santo Domingo to Panama City, there are around 30 to 31 flights per week. This means you usually have connections available on several days and at various times. Beyond the price, it is worth comparing flight duration, airline, and any potential additional fees.
When does the first flight from Santo Domingo to Panama City depart?
The earliest nonstop flight from Santo Domingo to Panama City usually departs at 5:47 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Panama City.
When does the last flight from Santo Domingo to Panama City depart?
The last nonstop flight from Santo Domingo to Panama City usually departs at 7:07 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.