Flight schedule from Santo Domingo (SDQ) to Panama City (PTY)
Select a travel date in the flight schedule for the route from Santo Domingo (SDQ) to Panama City (PTY) and compare affordable flight deals.
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- August 16 – 22, 2026
- August 23 – 29, 2026
- Aug 30 – Sep 5, 2026
- SDQPTYnonstop
- SDQPTYnonstop
- SDQPTYnonstop
- SDQPTYnonstop
- SDQPTY1 stopover
- SDQPTYnonstop
- SDQPTYnonstop
- SDQPTY1 stopover
- SDQPTY1 stopover
Important flight information
Frequently Asked Questions (FAQ)
A nonstop flight from Santo Domingo to Panama City typically takes around 2 hours 33 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 16 hours 5 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.
Yes, there are nonstop flights from Santo Domingo to Panama City, averaging around 4 to 5 flights per day, operated by, among others, Copa. If you want to fly without a layover, it is worth filtering specifically for nonstop flights when searching.
Direct flights from Santo Domingo to Panama City are operated by, among others, Copa. Connecting flights with one stop are also available, for example with Avianca (via Bogota). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.
Nonstop flights from Santo Domingo to Panama City operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
On the route from Santo Domingo to Panama City, there are on average around 4 to 5 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.
From Santo Domingo to Panama City, there are around 34 to 35 flights per week. This means you usually have connections available on several days and at various times. Beyond the price, it is worth comparing flight duration, airline, and any potential additional fees.
The earliest nonstop flight from Santo Domingo to Panama City usually departs at 5:50 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Panama City.
The last nonstop flight from Santo Domingo to Panama City usually departs at 7:07 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.