Question 1

How long is the flight from Santo Domingo to Panama City?

Accepted Answer

A nonstop flight from Santo Domingo to Panama City typically takes around 2 hours 33 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 16 hours 5 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.

Question 2

Are there nonstop flights from Santo Domingo to Panama City?

Accepted Answer

Yes, there are nonstop flights from Santo Domingo to Panama City, averaging around 4 to 5 flights per day, operated by, among others, Copa. If you want to fly without a layover, it is worth filtering specifically for nonstop flights when searching.

Question 3

Which airlines fly from Santo Domingo to Panama City?

Accepted Answer

Direct flights from Santo Domingo to Panama City are operated by, among others, Copa. Connecting flights with one stop are also available, for example with Avianca (via Bogota). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.

Question 4

On which days are there nonstop flights from Santo Domingo to Panama City?

Accepted Answer

Nonstop flights from Santo Domingo to Panama City operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.

Question 5

How many flights are there per day from Santo Domingo to Panama City?

Accepted Answer

On the route from Santo Domingo to Panama City, there are on average around 4 to 5 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.

Question 6

How many flights per week are there from Santo Domingo to Panama City?

Accepted Answer

From Santo Domingo to Panama City, there are around 33 to 34 flights per week. This means you usually have connections available on several days and at various times. Beyond the price, it is worth comparing flight duration, airline, and any potential additional fees.

Question 7

When does the first flight from Santo Domingo to Panama City depart?

Accepted Answer

The earliest nonstop flight from Santo Domingo to Panama City usually departs at 5:50 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Panama City.

Question 8

When does the last flight from Santo Domingo to Panama City depart?

Accepted Answer

The last nonstop flight from Santo Domingo to Panama City usually departs at 7:07 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.

	Outbound	Return	Airlines	Baggage	Price
Santo Domingo Panama City	Outbound 08/17/26 1 Stopover (BOG) AV0209, AV0040 12h 50min	Return 09/02/26 1 Stopover (BOG) AV0057, AV0208 16h 55min	Avianca	?	$545
Best option Santo Domingo Panama City	Outbound 08/17/26 direct CM0888 02h 32min	Return 09/02/26 direct CM0268 02h 30min	Copa Airlines		$701
Santo Domingo Panama City	Outbound 08/05/26 1 Stopover (BOG) AV0251, AV0060 23h 10min	Return 08/22/26 2 Stopovers (BOG, SJU) AV0041, AV0214, DM0503 13h 53min	Avianca		$549
Santo Domingo Panama City	Outbound 08/05/26 1 Stopover (BOG) AV0251, AV0040 06h 45min	Return 08/22/26 1 Stopover (BOG) AV0059, AV0250 06h 45min	Avianca		$549
Santo Domingo Panama City	Outbound 08/05/26 1 Stopover (BOG) AV0251, AV0040 06h 45min	Return 08/22/26 1 Stopover (BOG) AV0057, AV0208 16h 55min	Avianca		$552
Santo Domingo Panama City	Outbound 08/17/26 1 Stopover (BOG) AV0209, AV0040 12h 50min	Return 09/02/26 1 Stopover (BOG) AV0041, AV0250 12h 30min	Avianca	?	$566
Santo Domingo Panama City	Outbound 08/05/26 1 Stopover (BOG) AV0209, AV0040 12h 50min	Return 08/22/26 1 Stopover (BOG) AV0059, AV0250 06h 45min	Avianca		$583
Santo Domingo Panama City	Outbound 08/17/26 1 Stopover (BOG) AV0209, AV0040 12h 50min	Return 09/02/26 1 Stopover (BOG) AV0061, AV0250 25h 45min	Avianca	?	$601
Santo Domingo Panama City	Outbound 08/05/26 1 Stopover (BOG) AV0251, AV0040 06h 45min	Return 08/22/26 1 Stopover (BOG) AV0061, AV0208 19h 40min	Avianca	?	$614
Santo Domingo Panama City	Outbound 08/17/26 1 Stopover (BOG) AV0209, AV0056 26h 30min	Return 09/02/26 1 Stopover (BOG) AV0057, AV0208 16h 55min	Avianca		$616

Roundtrip from	544,64 $
Flight duration	min. 02:36 / max. 02:44
Return flight duration	min. 02:23/ max. 02:28
Distance	1478 km
Flights per week	38
Departure airport	Airport Santo Domingo, Dominican Republic (SDQ)
Departure country	Flights from Dominican Republic
Arrival airport	Airport Panama City-Tocumen International (PTY)
Destination country	Flights to Panama
Departure country - Arrival airport	Dominican Republic - Panama City-Tocumen International
Departure airport - Destination country	Santo Domingo, Dominican Republic - Panama

Flight Routes from Santo Domingo to Panama City

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Santo Domingo, Dominican Republic

Panama City-Tocumen International

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Flight information: Santo Domingo - Panama City

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