Question 1

How long is the flight from Santo Domingo to Panama City?

Accepted Answer

A nonstop flight from Santo Domingo to Panama City typically takes around 2 hours 33 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 16 hours 5 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.

Question 2

Are there nonstop flights from Santo Domingo to Panama City?

Accepted Answer

Yes, there are nonstop flights from Santo Domingo to Panama City, averaging around 4 to 5 flights per day, operated by, among others, Copa. If you want to fly without a layover, it is worth filtering specifically for nonstop flights when searching.

Question 3

Which airlines fly from Santo Domingo to Panama City?

Accepted Answer

Direct flights from Santo Domingo to Panama City are operated by, among others, Copa. These flights take you to Panama City nonstop, making them especially practical for short trips or weekend getaways. It is still worth comparing departure times and airline policies, as baggage rules and fees can vary.

Question 4

On which days are there nonstop flights from Santo Domingo to Panama City?

Accepted Answer

Nonstop flights from Santo Domingo to Panama City operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.

Question 5

How many flights are there per day from Santo Domingo to Panama City?

Accepted Answer

On the route from Santo Domingo to Panama City, there are on average around 4 to 5 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.

Question 6

How many flights per week are there from Santo Domingo to Panama City?

Accepted Answer

From Santo Domingo to Panama City, there are around 32 to 33 flights per week. This means you usually have connections available on several days and at various times. Beyond the price, it is worth comparing flight duration, airline, and any potential additional fees.

Question 7

When does the first flight from Santo Domingo to Panama City depart?

Accepted Answer

The earliest nonstop flight from Santo Domingo to Panama City usually departs at 5:50 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Panama City.

Question 8

When does the last flight from Santo Domingo to Panama City depart?

Accepted Answer

The last nonstop flight from Santo Domingo to Panama City usually departs at 7:07 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.

	Outbound	Return	Airlines	Baggage	Price
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0251, AV0040 06h 45min	Return 07/27/26 1 Stopover (BOG) AV0041, AV0208 06h 25min	Avianca		$585 found yesterday
Best option Santo Domingo Panama City	Outbound 07/13/26 direct CM0888 02h 32min	Return 07/27/26 direct CM0463 02h 31min	Copa Airlines		$917 found yesterday
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0251, AV0040 06h 45min	Return 07/27/26 1 Stopover (BOG) AV0041, AV0208 06h 25min	Avianca		$592 found yesterday
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0209, AV0040 12h 50min	Return 07/27/26 1 Stopover (BOG) AV0041, AV0208 06h 25min	Avianca	?	$607 found yesterday
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0209, AV0040 12h 50min	Return 07/27/26 1 Stopover (BOG) AV0057, AV0208 16h 55min	Avianca		$620 found yesterday
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0209, AV0058 21h 30min	Return 07/27/26 1 Stopover (BOG) AV0059, AV0250 06h 45min	Avianca	?	$639 found yesterday
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0209, AV0040 12h 50min	Return 07/27/26 1 Stopover (BOG) AV0057, AV0208 16h 55min	Avianca	?	$647 found yesterday
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0251, AV0040 06h 45min	Return 07/27/26 1 Stopover (BOG) AV0061, AV0208 19h 40min	Avianca	?	$653 found yesterday
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0209, AV0058 21h 30min	Return 07/27/26 1 Stopover (BOG) AV0057, AV0208 16h 55min	Avianca		$655 found yesterday
Santo Domingo Panama City	Outbound 07/13/26 1 Stopover (BOG) AV0251, AV0040 06h 45min	Return 07/27/26 1 Stopover (BOG) AV0059, AV0250 06h 45min	Avianca	?	$736 found yesterday

Roundtrip from	$585.00
Flight duration	min. 02:36 / max. 02:44
Return flight duration	min. 02:23/ max. 02:28
Distance	1478 km
Flights per week	38
Departure airport	Airport Santo Domingo, Dominican Republic (SDQ)
Departure country	Flights from Dominican Republic
Arrival airport	Airport Panama City-Tocumen International (PTY)
Destination country	Flights to Panama
Departure country - Arrival airport	Dominican Republic - Panama City-Tocumen International
Departure airport - Destination country	Santo Domingo, Dominican Republic - Panama

Flight Routes from Santo Domingo to Panama City

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Santo Domingo, Dominican Republic

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Flight information: Santo Domingo - Panama City

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