The flight route from Los Angeles (LAX) to San Francisco (SFO) is popular among all sorts of travelers- both business passengers and those on vacation- with over 47 flights daily. It will take you around 1 and a half hours to travel the 382 miles up the state. Airlines offering a direct flight are: American, Virgin America, Southwest, United and Delta.
There are several airlines offering a low-cost air ticket option so that you can have more to spend on your trip. The three that routinely offer good deals are United, Virgin America and American. As usual, tips for finding the lowest fare include early booking, avoiding school vacations and weekends and using a flight comparison site to help find good deals.
Once you have landed, getting around town is easy and, given that it's San Francisco, often stylish. BART operates a rapid rail service to northern San Mateo County, downtown and the East Bay. From the terminal use the Airtrain to get to the station. Alternatively, buses, taxis and shuttles are also available.