Flight Routes from Knoxville to Sioux Falls

Compare cheap outbound and return flights from Knoxville (TYS) to Sioux Falls (FSD) and find the best offer from numerous airlines and travel agencies.

Cheapest roundtrip flight: from€418
Flight distance: 1,390 km
Time difference: -1 hour

Flight schedule from Knoxville (TYS) to Sioux Falls (FSD)

Select a travel date in the flight schedule for the route from Knoxville (TYS) to Sioux Falls (FSD) and compare affordable flight deals.

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Matching outbound flightsTYS–FSD · 0 of 0

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Sep 27 – Oct 3, 2026
October 4 – 10, 2026
October 11 – 17, 2026

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Important flight information

Discover more flights around Knoxville and Sioux Falls

Departure airport	Airport Knoxville, TN (TYS)
Arrival airport	Airport Sioux Falls, SD (FSD)
Destination country	Flights to United States
Departure airport - Destination country	Knoxville, TN - United States

Alternative routes to United States

Flight Knoxville - Philadelphia from 340 $
Flight Knoxville - Chicago from 298 $
Flight Knoxville - Miami from 464 $
Flight Knoxville - Washington DC from 278 $
Flight Knoxville - New York from 353 $
Flight Knoxville - Boston from 318 $
Flight Knoxville - Fort Lauderdale from 178 $
Flight Knoxville - Phoenix - Sky Harbor from 372 $
Flight Knoxville - Newark from 353 $
Flight Knoxville - Denver from 374 $

Alternative flights to Sioux Falls

Flight Minneapolis - Sioux Falls from 535 $
Flight Phoenix-Mesa Gateway Airport - Sioux Falls from 241 $
Flight Fort Lauderdale - Sioux Falls from 516 $
Flight Lexington - Sioux Falls from 426 $
Flight Chicago - Sioux Falls from 309 $
Flight Orlando - Sioux Falls from 497 $
Flight Dallas - Sioux Falls from 440 $
Flight Tampa - Sioux Falls from 453 $
Flight Punta Gorda - Sioux Falls from 1.042 $
Flight Las Vegas - Sioux Falls from 333 $

Flight destinations with a similar price

Flight Knoxville - Punta Gorda from 382 $
Flight Knoxville - Moline from 421 $
Flight Knoxville - San Diego from 444 $
Flight Knoxville - Sarasota-Bradenton from 412 $
Flight Knoxville - La Crosse from 437 $
Flight Knoxville - Fayetteville from 441 $
Flight Knoxville - Saginaw from 416 $
Flight Knoxville - Austin from 396 $
Flight Knoxville - Charlotte from 422 $
Flight Knoxville - Memphis from 401 $