- Cheapest roundtrip flight
- from€298
- Fastest flight
- non-stop flights
- 1x / week
- Flight distance
- 746 km
- Time difference
- Airports in Chicago
- O'Hare International Airport, IL
- Midway International Airport, IL
- Rockford, IL
- Most popular airlines
- United Airlines
- American Airlines
- Allegiant Air
- United Airlines
Cheap flight offers from Knoxville to Chicago
sorted by price and recency
- – –TYS–CHI1 stopover–CHI–TYSnon-stop flight€298
- – –TYS–CHI1 stopover–CHI–TYSnon-stop flight€463
- – –TYS–CHI1 stopover–CHI–TYSnon-stop flight€384
- – –TYS–CHI1 stopover–CHI–TYSnon-stop flight€319
- – –TYS–CHI1 stopover
–CHI–TYS3 stopovers€1,146 - – –TYS–CHInon-stop flight–CHI–TYSnon-stop flight€465
Flight schedule from Knoxville (TYS) to Chicago (CHI)
Select a travel date in the flight schedule for the route from Knoxville (TYS) to Chicago (CHI) and compare affordable flight deals.
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Matching outbound flightsTYS–CHI · 30 of 30
fromto
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- November 8 – 14, 2026
- November 15 – 21, 2026
- November 22 – 28, 2026
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Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Knoxville to Chicago?
A nonstop flight from Knoxville to Chicago typically takes around 2 hours. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 9 hours 6 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.
Are there nonstop flights from Knoxville to Chicago?
Yes, there are nonstop flights from Knoxville to Chicago, although not necessarily every day. On average, around 1 to 2 flights per week are available. If you have flexibility with your travel dates, you will have an easier time finding a suitable nonstop connection.
Which airlines fly from Knoxville to Chicago?
Direct flights from Knoxville to Chicago are operated by, among others, United Airlines, American Airlines and Allegiant Air. Connecting flights with one stop are also available, for example with Allegiant Air (via Punta Gorda). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.
On which days are there nonstop flights from Knoxville to Chicago?
Nonstop flights from Knoxville to Chicago operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Knoxville to Chicago?
On the route from Knoxville to Chicago, there is less than one flight per day on average. The exact number can vary by day of the week and season. If you have flexibility with your travel dates, it is worth comparing several departure days.
How many flights per week are there from Knoxville to Chicago?
On the route from Knoxville to Chicago, there are only a few flights per week. It is therefore especially worthwhile to be flexible with your travel dates so you can more easily find a suitable departure day.
When does the first flight from Knoxville to Chicago depart?
The earliest nonstop flight from Knoxville to Chicago usually departs at 6:45 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Chicago.
When does the last flight from Knoxville to Chicago depart?
The last nonstop flight from Knoxville to Chicago usually departs at 1:59 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.