Flight Routes from Knoxville to Chicago O'Hare

Compare cheap outbound and return flights from Knoxville (TYS) to Chicago O'Hare (ORD) and find the best offer from numerous airlines and travel agencies.

Trip type
Cheapest roundtrip flight
from€298
Flight distance
765 km
Time difference

Cheap flight offers from Knoxville to Chicago O'Hare

sorted by price and recency
filters
  1. –
    American Airlines
    –
    TYS–ORD
    1 stopover
    American Airlines
    –
    ORD–TYS
    non-stop flight
    €298
  2. –
    American Airlines
    –
    TYS–ORD
    1 stopover
    American Airlines
    –
    ORD–TYS
    non-stop flight
    €463
  3. –
    American Airlines
    –
    TYS–ORD
    1 stopover
    American Airlines
    –
    ORD–TYS
    non-stop flight
    €384
  4. –
    American Airlines
    –
    TYS–ORD
    1 stopover
    American Airlines
    –
    ORD–TYS
    non-stop flight
    €319
  5. –
    Allegiant Air
    –
    TYS–ORD
    1 stopover
    United Airlines
    –
    ORD–TYS
    1 stopover
    €473
  6. –
    United Airlines
    –
    TYS–ORD
    non-stop flight
    United Airlines
    –
    ORD–TYS
    non-stop flight
    €465

Flight schedule from Knoxville (TYS) to Chicago O'Hare (ORD)

Select a travel date in the flight schedule for the route from Knoxville (TYS) to Chicago O'Hare (ORD) and compare affordable flight deals.

offers
Active filtersnone
Matching outbound flightsTYS–ORD · 28 of 28
fromto
dep.arr.
durationstopovers
  1. November 8 – 14, 2026
  2. November 15 – 21, 2026
  3. November 22 – 28, 2026
    1. TYSORD
      nonstop
      1. United Airlines
    2. TYSORD
      nonstop
      1. American Airlines
    3. TYSORD
      nonstop
      1. American Airlines
    4. TYSORD
      nonstop
      1. American Airlines
    5. TYSORD
      nonstop
      1. United Airlines
    6. TYSORD
      nonstop
      1. United Airlines
    7. TYSORD
      nonstop
      1. United Airlines
    8. TYSORD
      nonstop
      1. United Airlines
    9. TYSORD
      nonstop
      1. United Airlines
    10. TYSORD
      nonstop
      1. American Airlines
    11. TYSORD
      nonstop
      1. Royal Jordanian
    12. TYSORD
      nonstop
      1. American Airlines
    13. TYSORD
      nonstop
      1. American Airlines
    14. TYSORD
      nonstop
      1. Royal Jordanian
    15. TYSORD
      nonstop
      1. American Airlines

      Important flight information

      Discover more flights around Knoxville and Chicago O'Hare

      Departure airport Airport Knoxville, TN (TYS)
      Arrival airport Airport Chicago O'Hare International Airport, IL (ORD)
      Destination country Flights to United States
      Departure airport - Destination country Knoxville, TN - United States
      Departure airport - City-Code Knoxville, TN - Chicago
      Alternative routes to United States
      Alternative flights to Chicago O'Hare
      Flight destinations with a similar price
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