Flight Routes from Knoxville to San Diego

Compare cheap outbound and return flights from Knoxville (TYS) to San Diego (SAN) and find the best offer from numerous airlines and travel agencies.

Cheapest roundtrip flight: from€444
Flight distance: 3,058 km
Time difference: -3 hours

Flight schedule from Knoxville (TYS) to San Diego (SAN)

Select a travel date in the flight schedule for the route from Knoxville (TYS) to San Diego (SAN) and compare affordable flight deals.

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October 18 – 24, 2026
October 25 – 31, 2026
November 1 – 7, 2026

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Important flight information

Discover more flights around Knoxville and San Diego

Departure airport	Airport Knoxville, TN (TYS)
Arrival airport	Airport San Diego - Lindberg Field International, CA (SAN)
Destination country	Flights to United States
Departure airport - Destination country	Knoxville, TN - United States

Alternative routes to United States

Flight Knoxville - Philadelphia from 340 $US
Flight Knoxville - Miami from 464 $US
Flight Knoxville - Chicago from 298 $US
Flight Knoxville - New York from 353 $US
Flight Knoxville - Boston from 318 $US
Flight Knoxville - Washington DC from 278 $US
Flight Knoxville - Fort Lauderdale from 178 $US
Flight Knoxville - Newark from 353 $US
Flight Knoxville - Denver from 374 $US
Flight Knoxville - Phoenix - Sky Harbor from 372 $US

Alternative flights to San Diego

Flight New York - San Diego from 358 $US
Flight Las Vegas - San Diego from 111 $US
Flight San Francisco - San Diego from 143 $US
Flight Los Angeles - San Diego from 171 $US
Flight Orlando - San Diego from 366 $US
Flight Austin - San Diego from 190 $US
Flight Miami - San Diego from 500 $US
Flight Seattle-Tacoma - San Diego from 237 $US
Flight Portland-Oregon - San Diego from 314 $US
Flight Kona - San Diego from 546 $US

Flight destinations with a similar price

Flight San Diego - Berlin from 629 $US
Flight San Diego - Tokyo Narita from 823 $US
Flight San Diego - London Heathrow from 729 $US
Flight San Diego - London from 729 $US
Flight San Diego - Frankfurt from 758 $US
Flight San Diego - Montréal-Pierre Elliott Trudeau International from 557 $US
Flight San Diego - Tokyo from 823 $US
Flight San Diego - Panama City from 654 $US
Flight San Diego - Vancouver from 277 $US
Flight San Diego - Toronto from 538 $US

Flight destinations with a similar price

Flight Knoxville - Miami from 464 $US
Flight Knoxville - Sioux Falls from 418 $US
Flight Knoxville - La Crosse from 437 $US
Flight Knoxville - Fayetteville from 441 $US
Flight Knoxville - Sarasota-Bradenton from 412 $US
Flight Knoxville - Moline from 421 $US
Flight Knoxville - Chicago Midway from 420 $US
Flight Knoxville - Memphis from 401 $US
Flight Knoxville - Nashville from 401 $US
Flight Knoxville - Las Vegas from 460 $US