Flight Routes from Knoxville to La Crosse

Compare cheap outbound and return flights from Knoxville (TYS) to La Crosse (LSE) and find the best offer from numerous airlines and travel agencies.

Trip type
Cheapest roundtrip flight
from€437
Flight distance
1,091 km
Time difference

Cheap flight offers from Knoxville to La Crosse

sorted by price and recency
  1. –
    American Airlines
    –
    TYS–LSE
    1 stopover
    American Airlines
    –
    LSE–TYS
    1 stopover
    €576
  2. –
    American Airlines
    –
    TYS–LSE
    2 stopovers
    American Airlines
    –
    LSE–TYS
    1 stopover
    €496
  3. –
    American Airlines
    –
    TYS–LSE
    1 stopover
    American Airlines
    –
    LSE–TYS
    1 stopover
    €437

Flight schedule from Knoxville (TYS) to La Crosse (LSE)

Select a travel date in the flight schedule for the route from Knoxville (TYS) to La Crosse (LSE) and compare affordable flight deals.

offers
Active filtersnone
Matching outbound flightsTYS–LSE · 1 of 1
fromto
dep.arr.
durationstopovers
  1. November 8 – 14, 2026
  2. November 15 – 21, 2026
  3. November 22 – 28, 2026
    1. TYSLSE
      nonstop
      1. United Airlines

      Important flight information

      Discover more flights around Knoxville and La Crosse

      Departure airport Airport Knoxville, TN (TYS)
      Arrival airport Airport La Crosse, WI (LSE)
      Destination country Flights to United States
      Departure airport - Destination country Knoxville, TN - United States