- Fastest outbound flight
- Fastest inbound flight
- non-stop flights
- 271x / week
- Flight distance
- 419 km
- Time difference
- none
- Airports in Chicago
- O'Hare International Airport, IL
- Midway International Airport, IL
- Rockford, IL
- Most popular airlines
- United Airlines
- American Airlines
- Southwest Airlines
- United Airlines
Flight schedule from Chicago (CHI) to St. Louis (STL)
Select a travel date in the flight schedule for the route from Chicago (CHI) to St. Louis (STL) and compare affordable flight deals.
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Matching outbound flights44 of 44
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durationstopovers
- September 6 – 12, 2026
- September 13 – 19, 2026
- September 20 – 26, 2026
- MDWSTLnonstop
- MDWSTLnonstop
- ORDSTLnonstop
- MDWSTLnonstop
- ORDSTLnonstop
- ORDSTLnonstop
- MDWSTLnonstop
- MDWSTLnonstop
- MDWSTLnonstop
- ORDSTLnonstop
- ORDSTLnonstop
- ORDSTLnonstop
- MDWSTLnonstop
- ORDSTLnonstop
- ORDSTLnonstop
Tips and tricks to help you find cheap flights from Chicago to St. Louis
Favorite airline: Southern Airways Express
52 % of flights from Chicago to St. Louis are booked with Southern Airways Express.
Southern Airways Express
52 %
United Airlines
22 %
Spirit Airlines
11 %
Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Chicago to St. Louis?
A nonstop flight from Chicago to St. Louis typically takes around 1 hour 31 minutes. This makes the nonstop service the fastest and most convenient way to travel between Chicago and St. Louis. It is worth checking flight times when searching, as they can vary by airline and travel date.
Are there nonstop flights from Chicago to St. Louis?
Yes, there are nonstop flights from Chicago to St. Louis, averaging around 37 to 38 flights per day, operated by, among others, United Airlines, American Airlines and Southwest. If you want to fly without a layover, it is worth filtering specifically for nonstop flights when searching.
Which airlines fly from Chicago to St. Louis?
Direct flights from Chicago to St. Louis are operated by, among others, United Airlines, American Airlines and Southwest. These flights take you to St. Louis nonstop, making them especially practical for short trips or weekend getaways. It is still worth comparing departure times and airline policies, as baggage rules and fees can vary.
On which days are there nonstop flights from Chicago to St. Louis?
Nonstop flights from Chicago to St. Louis operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Chicago to St. Louis?
From Chicago to St. Louis, there are on average around 37 to 38 flights per day. This usually means you have a good choice of departure times. If you are flexible, you can easily compare times, prices, and airlines.
How many flights per week are there from Chicago to St. Louis?
From Chicago to St. Louis, there are around 265 to 266 flights per week. This means you usually have connections available on several days and at various times. Beyond the price, it is worth comparing flight duration, airline, and any potential additional fees.
When does the first flight from Chicago to St. Louis depart?
The earliest nonstop flight from Chicago to St. Louis usually departs at 5:40 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in St. Louis.
When does the last flight from Chicago to St. Louis depart?
The last nonstop flight from Chicago to St. Louis usually departs at 11:05 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.