Flight Routes from Chicago to Santiago de Chile

Compare cheap outbound and return flights from Chicago (CHI) to Santiago de Chile (SCL) and find the best offer from numerous airlines and travel agencies.

Trip type
Flight distance
8,555 km
Time difference
Airports in Chicago
  1. O'Hare International Airport, IL
  2. Midway International Airport, IL
  3. Rockford, IL

Flight schedule from Chicago (CHI) to Santiago de Chile (SCL)

Select a travel date in the flight schedule for the route from Chicago (CHI) to Santiago de Chile (SCL) and compare affordable flight deals.

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durationstopovers
  1. September 6 – 12, 2026
  2. September 13 – 19, 2026
  3. September 20 – 26, 2026
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        Tips and tricks to help you find cheap flights from Chicago to Santiago de Chile

        Favorite airline: LATAM Chile
        The majority of passengers on the route Chicago – Santiago de Chile prefer to fly with LATAM Chile.
        LATAM Chile
        31 %
        Copa
        27 %
        Spirit Airlines
        15 %
        Favourite connection: via Panama City
        The most popular route is via Panama City and is booked by 32 % of all travelers.
        Route
        bookings
        1 stopover Panama City-Tocumen International
        27h 08min, from 584 $
        32 %
        1 stopover Hartsfield-Jackson Atlanta International Airport, GA
        14h 08min, from 573 $
        27 %
        1 stopover New York - John F. Kennedy International Airport, NY
        13h 54min, from 674 $
        14 %

        Important flight information

        Discover more flights around Chicago and Santiago de Chile

        Departure airport Airport Chicago-IL, all airports (CHI)
        Arrival airport Airport Santiago de Chile - Arturo Merino Benitez (SCL)
        Destination country Flights to Chile
        Departure airport - Destination country Chicago-IL, all airports - Chile
        Alternative flights to Santiago de Chile
        Flight destinations with a similar price