Flights from Chicago to Santiago de Chile

Our cheapest offers for flights from Chicago to Santiago de Chile

Here you can compare cheap flights from Chicago (CHI) to Santiago de Chile (SCL) for one-way or return trips. The following offers were searched for and found on idealo during the last few days. Or start your own flight search to Santiago de Chile. Prices and availability may change at any time.

Outbound Return Airlines Shop Baggage Price
Chicago
Santiago de Chile
Outbound
10/18/25
1 Stopover (BOG)
AV0263, AV0115
21h 50min
Return
10/24/25
1 Stopover (BOG)
AV0116, AV0262
23h 45min
Avianca
$601
Best option
Chicago
Santiago de Chile
Outbound
09/19/25
1 Stopover (BOG)
AV0263, AV0097
12h 40min
Return
09/29/25
1 Stopover (BOG)
AV0116, AV0262
23h 45min
Avianca ?
$641
Chicago
Santiago de Chile
Outbound
06/08/25
2 Stopovers (DCA, MIA)
AA0311, AA0897, AA0957
16h 20min
Return
06/29/25
2 Stopovers (MIA, CLT)
AA0912, AA0969, AA1052
17h 15min
American Airlines
$892
Chicago
Santiago de Chile
Outbound
06/07/25
3 Stopovers (SAL, PTY, MDE)
AV0409, AV0323, AV0323, AV0147
30h 25min
Return
06/23/25
1 Stopover (BOG)
AV0240, AV0262
14h 20min
Avianca ?
$621
Chicago
Santiago de Chile
Outbound
09/19/25
1 Stopover (BOG)
AV0263, AV0115
21h 50min
Return
09/29/25
1 Stopover (BOG)
AV0116, AV0262
23h 45min
Avianca
$651
Chicago
Santiago de Chile
Outbound
06/07/25
2 Stopovers (SAL, MDE)
AV0409, AV0323, AV0147
30h 25min
Return
06/23/25
2 Stopovers (PUJ, MIA)
DM6173, DM5100, NK2194
19h 21min
Avianca
$655
Chicago
Santiago de Chile
Outbound
06/08/25
2 Stopovers (SJO, BOG)
AV0631, AV0693, AV0115
20h 40min
Return
06/29/25
1 Stopover (BOG)
AV0116, AV0262
23h 45min
Avianca
$670
Chicago
Santiago de Chile
Outbound
06/07/25
2 Stopovers (SAL, MDE)
AV0409, AV0323, AV0147
30h 25min
Return
06/23/25
1 Stopover (BOG)
AV0240, AV0262
14h 20min
Avianca
$695
Chicago
Santiago de Chile
Outbound
06/08/25
1 Stopover (BOG)
AV0263, AV0115
21h 50min
Return
06/12/25
3 Stopovers (LIM, CUN, MEX)
H25802, H25553, Y40115, Y40700
32h 32min
Avianca
$728
Chicago
Santiago de Chile
Outbound
06/18/25
1 Stopover (MIA)
AA2323, AA0957
13h 20min
Return
07/15/25
2 Stopovers (MIA, PHL)
AA0912, AA0551, AA0865
20h 35min
American Airlines ?
$729
Prices based on recent searches, subject to last-minute changes
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Tips and tricks to help you find cheap flights from Chicago to Santiago de Chile

Favorite airline: LATAM Chile
The majority of passengers on the route Chicago – Santiago de Chile prefer to fly with LATAM Chile.
LATAM Chile
31 %
Copa
27 %
Spirit Airlines
15 %
Favourite connection: via Panama City
The most popular route is via Panama City and is booked by 32 % of all travelers.
Route
bookings
1 stopover Panama City-Tocumen International
27h 08min, from $ 584
32 %
1 stopover Hartsfield-Jackson Atlanta International Airport, GA
14h 08min, from $ 573
27 %
1 stopover New York - John F. Kennedy International Airport, NY
13h 54min, from $ 674
14 %

Important flight information

Flight information: Chicago - Santiago de Chile

Roundtrip from $ 600,29
Distance 8555 km
Departure airport Airport Chicago-IL all Airports (ORD, MDW, RFD) (CHI)
Arrival airport Airport Santiago de Chile - Arturo Merino Benitez (SCL)
Destination country Flights to Chile
Alternative flights to Santiago de Chile
Flight destinations with a similar price