- Miami (MIA) Madrid (MAD)
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1–2 Non-stop flights per dayat least 7h 20minfrom $521 - Atlanta (ATL) Madrid (MAD)
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1 Non-stop flight per dayat least 7h 5minfrom $550 - Boston (BOS) Madrid (MAD)
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1–2 Non-stop flights per dayat least 6hfrom $345 - Washington DC (IAD) Madrid (MAD)
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up to 1 Non-stop flight per dayat least 6h 10minfrom $346 - Los Angeles (LAX) Madrid (MAD)
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up to 1 Non-stop flight per dayat least 10hfrom $1,013 - San Francisco (SFO) Madrid (MAD)
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4 Non-stop flights per weekat least 11h 25minfrom $271 - Dallas (DFW) Madrid (MAD)
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1 Non-stop flight per dayat least 7h 50minfrom $738 - Charlotte (CLT) Madrid (MAD)
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1 Non-stop flight per dayat least 6h 45minfrom $527