Flights from St. Louis to San Diego

Our cheapest offers for flights from St. Louis to San Diego

Here you can compare cheap flights from St. Louis (STL) to San Diego (SAN) for one-way or return trips. The following offers were searched for and found on idealo during the last few days. Or start your own flight search to San Diego. Prices and availability may change at any time.

Outbound Return Airlines Shop Baggage Price
St. Louis
San Diego
Outbound
04/26/25
1 Stopover (SEA)
AS0473, AS1096
09h 17min
Return
05/23/25
1 Stopover (SEA)
AS1199, AS0388
17h 02min
Alaska Airlines ?
$406
Best option
St. Louis
San Diego
Outbound
04/26/25
1 Stopover (SEA)
AS0473, AS1096
09h 17min
Return
05/23/25
1 Stopover (SEA)
AS1137, AS0472
10h 26min
Alaska Airlines
$410
St. Louis
San Diego
Outbound
04/26/25
1 Stopover (IAH)
UA6345, UA2486
06h 52min
Return
05/23/25
1 Stopover (SFO)
UA0505, UA0336
19h 25min
United Airlines ?
$407
St. Louis
San Diego
Outbound
04/26/25
1 Stopover (SFO)
UA1315, UA2861
08h 36min
Return
05/23/25
1 Stopover (SFO)
UA0505, UA0336
19h 25min
United Airlines ?
$448
St. Louis
San Diego
Outbound
04/26/25
1 Stopover (SEA)
AS0473, AS1096
09h 17min
Return
05/23/25
1 Stopover (SEA)
AS1154, AS0291
09h 37min
Alaska Airlines ?
$482
Prices based on recent searches, subject to last-minute changes
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Tips and tricks to help you find cheap flights from St. Louis to San Diego

Favorite airline: Spirit Airlines
The most popular airline for flights from St. Louis to San Diego is Spirit Airlines.
Spirit Airlines
40 %
Frontier Airlines
33 %
Delta
20 %
Favourite connection: via Las Vegas
On this route, flights with a stopover in Las Vegas are the most popular.
Route
bookings
1 stopover Las Vegas - McCarran International Airport, NV
09h 06min, from $254
50 %
1 stopover Denver International Airport, CO
06h 23min, from $217
42 %
1 stopover Detroit Metropolitan Wayne County Airport, MI
09h 54min, from $342
8 %

Important flight information

Flight information: St. Louis - San Diego

Roundtrip from $405.77
Flight duration min. 04:05 / max. 14:00
Return flight duration min. 03:20/ max. 08:00
Distance 2504 km
Flights per week 48
Departure airport Airport St. Louis - Lambert International Airport (STL)
Arrival airport Airport San Diego - Lindberg Field International, CA (SAN)
Destination country Flights to United States
Alternative routes to United States
Alternative flights to San Diego
Flight destinations with a similar price
Flight destinations with a similar price