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Tips and tricks to help you find cheap flights from Santo Domingo to Holguin

Favorite airline: Avianca
The most popular airline for flights from Santo Domingo to Holguin is Avianca.
Avianca
50 %
Copa
38 %
InterCaribbean Airways
12 %
Favourite connection: via Bogota and Panama City
On this route, flights with a stopover in Bogota and Panama City are the most popular.
Route
bookings
2 stopovers Bogota Panama City-Tocumen International
41h 45min, from $1,010
50 %
1 stopover Panama City-Tocumen International
27h 06min, from $860
38 %
2 stopovers Kingston-Norman Manley Panama City-Tocumen International
45h 30min, from $963
12 %