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Tips and tricks to help you find cheap flights from Santo Domingo to Santiago de Cuba

Favorite airline: Copa
90 % of flights booked on the route from Santo Domingo to Santiago de Cuba are booked with Copa and InterCaribbean Airways.
55 %
InterCaribbean Airways
35 %
Tip: book 4 weeks before departure
Save up to 44 % by booking flights 4 weeks before departure.
31 days before departure
Cheapest weekday: Thursday
On this route flights are cheapest on Thursday when a ticket costs $447.00 on average.
Direct flights are the cheapest connection
Compared to direct flights, flights with a stopover on this route are on average 29 % more expensive.
non stop flight
1 stop
2 stops
01h 41min
10h 10min
26h 56min
Favourite connection: via Panama City and Havana
On this route, flights with a stopover in Panama City and Havana are the most popular.
2 stopovers Panama City-Tocumen International Havana-Jose Marti International
26h 56min, from $633
55 %
Direct flights
01h 41min, from $447
35 %
1 stopover Havana-Jose Marti International
10h 10min, from $696
10 %
Flight information Santo Domingo - Santiago de Cuba
Flight details Santo Domingo - Santiago de Cuba
  • Flight duration: min. 01:20 / max. 01:20
  • Distance: 670 km
  • Flights per week: 2
  • Return flight duration: min. 01:20 / max. 01:20