Flight Routes from San Francisco to Santo Domingo

Compare cheap outbound and return flights from San Francisco (SFO) to Santo Domingo (SDQ) and find the best offer from numerous airlines and travel agencies.

Trip type
Flight distance
5,520 km
Time difference

Flight schedule from San Francisco (SFO) to Santo Domingo (SDQ)

Select a travel date in the flight schedule for the route from San Francisco (SFO) to Santo Domingo (SDQ) and compare affordable flight deals.

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Matching outbound flightsSFO–SDQ · 0 of 0
fromto
dep.arr.
durationstopovers
  1. Sep 27 – Oct 3, 2026
  2. October 4 – 10, 2026
  3. October 11 – 17, 2026
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        Tips and tricks to help you find cheap flights from San Francisco to Santo Domingo

        Favorite airline: e.g. Aeroméxico, Avianca
        Aeroméxico is the most popular airline for flights from San Francisco to Santo Domingo.
        Aeroméxico
        36 %
        Avianca
        36 %
        Copa
        27 %
        Favourite connection: via Panama City
        The most popular route is via Panama City and is booked by 50 % of all travelers.
        Route
        bookings
        1 stopover Panama City-Tocumen International
        20h 22min, from 551 US$
        50 %
        2 stopovers San Salvador Guatemala City
        13h 05min, from 525 US$
        33 %
        2 stopovers Guadalajara Mexico City-Juarez International
        13h 39min, from 586 US$
        17 %

        Important flight information

        Discover more flights around San Francisco and Santo Domingo

        Departure airport Airport San Francisco International Airport, CA (SFO)
        Arrival airport Airport Santo Domingo, Dominican Republic (SDQ)
        Destination country Flights to Dominican Republic
        Departure airport - Destination country San Francisco International Airport, CA - Dominican Republic
        Alternative flights to Santo Domingo
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