Flights from San Francisco to Santo Domingo

Our cheapest offers for flights from San Francisco to Santo Domingo

Here you can compare cheap flights from San Francisco (SFO) to Santo Domingo (SDQ) for one-way or return trips. The following offers were searched for and found on idealo during the last few days. Or start your own flight search to Santo Domingo. Prices and availability may change at any time.

Outbound Return Airlines Shop Baggage Price
Best option
San Francisco
Santo Domingo
Outbound
04/26/25
1 Stopover (PTY)
CM0383, CM0107
22h 00min
Return
05/23/25
1 Stopover (PTY)
CM0267, CM0408
12h 30min
Copa Airlines ?
$544
San Francisco
Santo Domingo
Outbound
04/26/25
1 Stopover (PTY)
CM0383, CM0107
22h 00min
Return
05/23/25
1 Stopover (PTY)
CM0267, CM0408
12h 30min
Copa Airlines ?
$566
San Francisco
Santo Domingo
Outbound
04/26/25
1 Stopover (PTY)
CM0383, CM0107
22h 00min
Return
05/23/25
1 Stopover (PTY)
CM0267, CM0408
12h 30min
Copa Airlines ?
$593
San Francisco
Santo Domingo
Outbound
04/26/25
1 Stopover (SAL)
AV0561, DM4501
10h 55min
Return
05/23/25
2 Stopovers (MEX, GDL)
AM0655, AM0230, AM0622
52h 35min
Avianca, AraJet
$601
San Francisco
Santo Domingo
Outbound
04/26/25
1 Stopover (MIA)
AA2799, AA2367
11h 33min
Return
05/23/25
1 Stopover (MIA)
AA2171, AA2753
21h 57min
American Airlines ?
$689
San Francisco
Santo Domingo
Outbound
04/26/25
1 Stopover (MIA)
AA2111, AA1237
18h 32min
Return
05/23/25
1 Stopover (MIA)
AA1237, AA2035
10h 28min
American Airlines ?
$734
San Francisco
Santo Domingo
Outbound
04/26/25
2 Stopovers (GDL, MEX)
AM0623, AM0259, AM0654
13h 39min
Return
05/23/25
1 Stopover (MEX)
AM0655, AM0664
13h 24min
Aeroméxico
$897
Prices based on recent searches, subject to last-minute changes
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Tips and tricks to help you find cheap flights from San Francisco to Santo Domingo

Favorite airline: e.g. Aeroméxico, Avianca
Aeroméxico is the most popular airline for flights from San Francisco to Santo Domingo.
Aeroméxico
36 %
Avianca
36 %
Copa
27 %
Favourite connection: via Panama City
The most popular route is via Panama City and is booked by 50 % of all travelers.
Route
bookings
1 stopover Panama City-Tocumen International
20h 22min, from $551
50 %
2 stopovers San Salvador Guatemala City
13h 05min, from $525
33 %
2 stopovers Guadalajara Mexico City-Juarez International
13h 39min, from $586
17 %

Important flight information

Flight information: San Francisco - Santo Domingo

Roundtrip from $543.09
Distance 5520 km
Departure airport Airport San Francisco International Airport, CA (SFO)
Arrival airport Airport Santo Domingo, Dominican Republic (SDQ)
Destination country Flights to Dominican Republic
Alternative routes to Dominican Republic
Alternative flights to Santo Domingo
Flight destinations with a similar price