Outbound | Return | Airlines | Shop | Baggage | Price | ||
---|---|---|---|---|---|---|---|
Best option San Francisco Santo Domingo | Outbound 10/18/25 1 Stopover (ATL) F91448, F90030 12h 22min | Return 11/17/25 1 Stopover (JFK) B62510, B60015 15h 21min | | ![]() | ? | $424 | |
San Francisco Santo Domingo | Outbound 09/19/25 4 Stopovers (MSP, DTW, FLL, MCO) SY0396, NK2383, NK3721, NK0196, NK1567 28h 52min | Return 09/29/25 3 Stopovers (MIA, DTW, MSP) DM2100, NK0292, NK2388, SY0393 28h 43min | | ![]() | $554 | ||
San Francisco Santo Domingo | Outbound 09/04/25 2 Stopovers (SAL, BOG) AV0561, AV0071, AV0250 38h 10min | Return 09/28/25 2 Stopovers (BOG, SAL) AV0251, AV0366, AV0562 21h 25min | | ![]() | $642 | ||
San Francisco Santo Domingo | Outbound 10/18/25 1 Stopover (ATL) F91448, F90030 12h 22min | Return 11/17/25 2 Stopovers (BOG, SAL) AV0209, AV0130, AV0560 38h 05min | | ![]() | $502 | ||
San Francisco Santo Domingo | Outbound 10/18/25 1 Stopover (ATL) F91448, F90030 12h 22min | Return 11/17/25 2 Stopovers (BOG, SAL) AV0209, AV0130, AV0560 38h 05min | | ![]() | $508 | ||
San Francisco Santo Domingo | Outbound 09/19/25 1 Stopover (PTY) CM0383, CM0298 32h 42min | Return 09/29/25 1 Stopover (PTY) CM0299, CM0382 12h 31min | | ![]() | ? | $541 | |
San Francisco Santo Domingo | Outbound 09/19/25 1 Stopover (JFK) B60816, B61009 11h 52min | Return 09/29/25 1 Stopover (BOS) B61930, B60733 13h 34min | | ![]() | ? | $544 | |
San Francisco Santo Domingo | Outbound 07/25/25 2 Stopovers (PHX, MIA) AA2414, AA3044, AA1856 21h 00min | Return 08/17/25 1 Stopover (MIA) AA1856, AA2426 13h 56min | | ![]() | ? | $639 | |
San Francisco Santo Domingo | Outbound 09/19/25 2 Stopovers (SEA, MIA) AS0922, AS0305, DM2105 21h 56min | Return 09/29/25 2 Stopovers (MIA, SEA) DM2100, AS0305, AS1166 27h 13min | | ![]() | ? | $642 | |
San Francisco Santo Domingo | Outbound 09/19/25 1 Stopover (PTY) CM0383, CM0298 32h 42min | Return 09/29/25 1 Stopover (PTY) CM0299, CM0382 12h 31min | | ![]() | ? | $643 |
Airline
- American Airlines
- Frontier Airlines
- Copa Airlines
- United Airlines
- Aeroméxico
Tips and tricks to help you find cheap flights from San Francisco to Santo Domingo
Favorite airline: e.g. Aeroméxico, Avianca
Aeroméxico is the most popular airline for flights from San Francisco to Santo Domingo.

Aeroméxico
36 %

Avianca
36 %

Copa
27 %
Favourite connection: via Panama City
The most popular route is via Panama City and is booked by 50 % of all travelers.
Route
bookings
1 stopover Panama City-Tocumen International
20h 22min, from $551
50 %
2 stopovers San Salvador Guatemala City
13h 05min, from $525
33 %
2 stopovers Guadalajara Mexico City-Juarez International
13h 39min, from $586
17 %
Important flight information
Flight information: San Francisco - Santo Domingo
Roundtrip from | $423.83 |
---|---|
Distance | 5520 km |
Departure airport | Airport San Francisco International Airport, CA (SFO) |
Arrival airport | Airport Santo Domingo, Dominican Republic (SDQ) |
Destination country | Flights to Dominican Republic |
Alternative routes to Dominican Republic
- Flight San Francisco - Punta Cana from $460
Alternative flights to Santo Domingo
- Flight Boston - Santo Domingo from $347
- Flight Fort Lauderdale - Santo Domingo from $279
- Flight Miami - Santo Domingo from $204
- Flight New York - Santo Domingo from $358
- Flight Orlando - Santo Domingo from $253
- Flight Baltimore - Santo Domingo from $294
- Flight Newark - Santo Domingo from $288
- Flight Philadelphia - Santo Domingo from $333
- Flight New York - Santo Domingo from $336
- Flight Chicago O'Hare - Santo Domingo from $358
Flight destinations with a similar price
- Flight Santo Domingo - Frankfurt from $1,055
Flight destinations with a similar price
- Flight San Francisco - Brussels from $460
- Flight San Francisco - Prague from $460
- Flight San Francisco - Copenhagen from $457
- Flight San Francisco - Punta Cana from $460
- Flight San Francisco - Barcelona from $393
- Flight San Francisco - Madrid from $424
- Flight San Francisco - San Pedro Sula from $391
- Flight San Francisco - Milan-Malpensa from $440
- Flight San Francisco - Milan from $440
- Flight San Francisco - Cancun from $401