Flight Routes from San Diego to St. Louis

Compare cheap outbound and return flights from San Diego (SAN) to St. Louis (STL) and find the best offer from numerous airlines and travel agencies.

Trip type
Fastest outbound flight
Fastest inbound flight
non-stop flights
30x / week
Flight distance
2,504 km
Time difference

Flight schedule from San Diego (SAN) to St. Louis (STL)

Select a travel date in the flight schedule for the route from San Diego (SAN) to St. Louis (STL) and compare affordable flight deals.

offers
Active filtersnone
Matching outbound flights6 of 6
fromto
dep.arr.
durationstopovers
  1. September 13 – 19, 2026
  2. September 20 – 26, 2026
  3. Sep 27 – Oct 3, 2026
    1. SANSTL
      nonstop
      1. Southwest Airlines
    2. SANSTL
      nonstop
      1. Southwest Airlines
    3. SANSTL
      nonstop
      1. Southwest Airlines
    4. SANSTL
      nonstop
      1. Southwest Airlines
    5. SANSTL
      nonstop
      1. Southwest Airlines
    6. SANSTL
      nonstop
      1. Southwest Airlines

      Tips and tricks to help you find cheap flights from San Diego to St. Louis

      Favorite airline: Spirit Airlines
      The favorite airline for flights from San Diego to St. Louis is Spirit Airlines.
      Spirit Airlines
      37 %
      Frontier Airlines
      21 %
      Delta
      16 %
      Favourite connection: via Las Vegas
      The most popular route is via Las Vegas and is booked by 50 % of all travelers.
      Route
      bookings
      1 stopover Las Vegas - McCarran International Airport, NV
      11h 22min, from 219 $US
      50 %
      1 stopover Denver International Airport, CO
      21h 51min, from 235 $US
      25 %
      1 stopover Seattle-Tacoma International Airport, WA
      08h 41min, from 317 $US
      19 %

      Important flight information

      Discover more flights around San Diego and St. Louis

      Departure airport Airport San Diego - Lindberg Field International, CA (SAN)
      Arrival airport Airport St. Louis - Lambert International Airport (STL)
      Destination country Flights to United States
      Departure airport - Destination country San Diego - Lindberg Field International, CA - United States
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