Flight Routes from Portland to Des Moines

Compare cheap outbound and return flights from Portland (PWM) to Des Moines (DSM) and find the best offer from numerous airlines and travel agencies.

Trip type
Cheapest roundtrip flight
from€654
Fastest flight
non-stop flights
6x / week
Flight distance
1,922 km
Time difference

Cheap flight offers from Portland-ME to Des Moines

sorted by price and recency
filters
  1. –
    American Airlines
    –
    PWM–DSM
    1 stopover
    American Airlines
    –
    DSM–PWM
    1 stopover
    €865
  2. –
    American Airlines
    –
    PWM–DSM
    1 stopover
    American Airlines
    –
    DSM–PWM
    2 stopovers
    €663
  3. –
    United Airlines
    –
    PWM–DSM
    1 stopover
    United Airlines
    –
    DSM–PWM
    1 stopover
    €654
  4. –
    Breeze Airways
    –
    PWM–DSM
    2 stopovers
    United Airlines
    –
    DSM–PWM
    4 stopovers
    €975

Flight schedule from Portland (PWM) to Des Moines (DSM)

Select a travel date in the flight schedule for the route from Portland (PWM) to Des Moines (DSM) and compare affordable flight deals.

offers
Active filtersnone
Matching outbound flightsPWM–DSM · 1 of 1
fromto
dep.arr.
durationstopovers
  1. November 22 – 28, 2026
  2. Nov 29 – Dec 5, 2026
  3. December 6 – 12, 2026
    No flights could be found for the active filters.
    1. PWMDSM
      nonstop
      1. United Airlines

      Important flight information

      Discover more flights around Portland and Des Moines

      Departure airport Airport Portland, ME (PWM)
      Arrival airport Airport Des Moines, IA (DSM)
      Destination country Flights to United States
      Departure airport - Destination country Portland, ME - United States
      Alternative routes to United States
      Alternative flights to Des Moines
      Flight destinations with a similar price