Flight Routes from Chicago to Des Moines

Compare cheap outbound and return flights from Chicago (CHI) to Des Moines (DSM) and find the best offer from numerous airlines and travel agencies.

Trip type
Cheapest roundtrip flight
from€387
Fastest flight
non-stop flights
95x / week
Flight distance
503 km
Time difference
none
Airports in Chicago
  1. O'Hare International Airport, IL
  2. Midway International Airport, IL
  3. Rockford, IL

Flight schedule from Chicago (CHI) to Des Moines (DSM)

Select a travel date in the flight schedule for the route from Chicago (CHI) to Des Moines (DSM) and compare affordable flight deals.

offers
Active filtersnone
Matching outbound flightsCHI–DSM · 19 of 19
fromto
dep.arr.
durationstopovers
  1. October 4 – 10, 2026
  2. October 11 – 17, 2026
  3. October 18 – 24, 2026
    1. ORDDSM
      nonstop
      1. American Airlines
    2. ORDDSM
      nonstop
      1. United Airlines
    3. MDWDSM
      nonstop
      1. Southwest Airlines
    4. MDWDSM
      nonstop
      1. Southwest Airlines
    5. MDWDSM
      nonstop
      1. Southwest Airlines
    6. ORDDSM
      nonstop
      1. United Airlines
    7. ORDDSM
      nonstop
      1. United Airlines
    8. ORDDSM
      nonstop
      1. American Airlines
    9. ORDDSM
      nonstop
      1. United Airlines
    10. ORDDSM
      nonstop
      1. United Airlines
    11. ORDDSM
      nonstop
      1. United Airlines
    12. ORDDSM
      nonstop
      1. American Airlines
    13. MDWDSM
      nonstop
      1. Southwest Airlines
    14. ORDDSM
      nonstop
      1. United Airlines
    15. ORDDSM
      nonstop
      1. American Airlines

      Important flight information

      Discover more flights around Chicago and Des Moines

      Departure airport Airport Chicago-IL, all airports (CHI)
      Arrival airport Airport Des Moines, IA (DSM)
      Destination country Flights to United States
      Departure airport - Destination country Chicago-IL, all airports - United States
      Alternative routes to United States
      Alternative flights to Des Moines
      Flight destinations with a similar price