Flight Routes from Panama City to Santiago de Chile

Compare cheap outbound and return flights from Panama City (PTY) to Santiago de Chile (SCL) and find the best offer from numerous airlines and travel agencies.

Trip type
Cheapest roundtrip flight
from€685
Fastest flight
non-stop flights
44x / week
Flight distance
4,814 km
Time difference

Flight schedule from Panama City (PTY) to Santiago de Chile (SCL)

Select a travel date in the flight schedule for the route from Panama City (PTY) to Santiago de Chile (SCL) and compare affordable flight deals.

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Matching outbound flightsPTY–SCL · 7 of 7
fromto
dep.arr.
durationstopovers
  1. October 4 – 10, 2026
  2. October 11 – 17, 2026
  3. October 18 – 24, 2026
    1. PTYSCL
      nonstop
      1. Copa Airlines
    2. PTYSCL
      nonstop
      1. Copa Airlines
    3. PTYSCL
      nonstop
      1. Copa Airlines
    4. PTYSCL
      nonstop
      1. Copa Airlines
    5. PTYSCL
      nonstop
      1. Copa Airlines
    6. PTYSCL
      nonstop
      1. Copa Airlines
    7. PTYSCL
      nonstop
      1. Copa Airlines

      Tips and tricks to help you find cheap flights from Panama City to Santiago de Chile

      Favorite airline: Avianca
      100 % of travelers choose to book flights on this route with Avianca and Copa.
      Avianca
      70 %
      Copa
      30 %
      Stopover flights are the cheapest connection
      Flights with a stopover are on average $290.00 cheaper than direct flights.
      non stop flight
      1 stop
      06h 36min
      14h 45min
      $642
      $352
      Favourite connection: via Bogota
      70 % of booked tickets on this route are for flights with a transfer in Bogota.
      Route
      bookings
      1 stopover Bogota
      14h 45min, from $352
      70 %
      Direct flights
      06h 36min, from $642
      30 %

      Important flight information

      Discover more flights around Panama City and Santiago de Chile

      Departure airport Airport Panama City-Tocumen International (PTY)
      Departure country Flights from Panama
      Arrival airport Airport Santiago de Chile - Arturo Merino Benitez (SCL)
      Destination country Flights to Chile
      Departure country - Arrival airport Panama - Santiago de Chile - Arturo Merino Benitez
      Departure airport - Destination country Panama City-Tocumen International - Chile
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