Flights from Panama City to Santiago de Chile

Our cheapest offers for flights from Panama City to Santiago de Chile

Here you can compare cheap flights from Panama City (PTY) to Santiago de Chile (SCL) for one-way or return trips. The following offers were searched for and found on idealo during the last few days. Or start your own flight search to Santiago de Chile. Prices and availability may change at any time.

Outbound Return Airlines Shop Baggage Price
Panama City
Santiago de Chile
Outbound
04/03/26
1 Stopover (BOG)
AV0057, AV0115
14h 20min
Return
04/16/26
1 Stopover (BOG)
AV0240, AV0056
22h 15min
Avianca
$551
Best option
Panama City
Santiago de Chile
Outbound
04/03/26
direct
CM0474
06h 49min
Return
04/16/26
direct
CM0276
06h 44min
Copa Airlines ?
$591
Panama City
Santiago de Chile
Outbound
01/17/26
1 Stopover (BOG)
AV0059, AV0097
17h 45min
Return
02/12/26
1 Stopover (BOG)
AV0116, AV0040
10h 35min
Avianca ?
$593
Panama City
Santiago de Chile
Outbound
01/17/26
1 Stopover (BOG)
AV0061, AV0115
22h 25min
Return
02/12/26
1 Stopover (BOG)
AV0098, AV0060
11h 30min
Avianca
$599
Panama City
Santiago de Chile
Outbound
01/17/26
1 Stopover (BOG)
AV0057, AV0097
09h 40min
Return
02/12/26
1 Stopover (BOG)
AV0116, AV0040
10h 35min
Avianca
$601
Panama City
Santiago de Chile
Outbound
01/17/26
direct
CM0395
06h 32min
Return
02/12/26
direct
CM0174
06h 51min
Copa Airlines ?
$625
Panama City
Santiago de Chile
Outbound
04/03/26
2 Stopovers (SJO, BOG)
AV0323, AV0131, AV0097
13h 45min
Return
04/16/26
1 Stopover (BOG)
AV0240, AV8380
11h 15min
Avianca ?
$690
Panama City
Santiago de Chile
Outbound
04/03/26
direct
CM0474
06h 49min
Return
04/16/26
direct
CM0276
06h 44min
Copa Airlines ?
$695
Panama City
Santiago de Chile
Outbound
01/17/26
1 Stopover (BOG)
AV0057, AV0097
09h 40min
Return
02/12/26
2 Stopovers (BOG, SJO)
AV0240, AV0696, AV0322
15h 20min
Avianca ?
$710
Panama City
Santiago de Chile
Outbound
01/17/26
1 Stopover (LIM)
CM0838, H20805
08h 40min
Return
02/12/26
3 Stopovers (LIM, MIA, IAH)
H20806, H85590, UA1216, UA1916
52h 10min
Copa Airlines, Sky Airline ?
$1,224
Prices based on recent searches, subject to last-minute changes
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Tips and tricks to help you find cheap flights from Panama City to Santiago de Chile

Favorite airline: Avianca
100 % of travelers choose to book flights on this route with Avianca and Copa.
Avianca
70 %
Copa
30 %
Stopover flights are the cheapest connection
Flights with a stopover are on average $290.00 cheaper than direct flights.
non stop flight
1 stop
06h 36min
14h 45min
$ 642
$ 352
Favourite connection: via Bogota
70 % of booked tickets on this route are for flights with a transfer in Bogota.
Route
bookings
1 stopover Bogota
14h 45min, from $ 352
70 %
Direct flights
06h 36min, from $ 642
30 %

Important flight information

Flight information: Panama City - Santiago de Chile

Roundtrip from $ 550,30
Flight duration min. 06:26 / max. 06:39
Return flight duration min. 06:46/ max. 07:00
Distance 4814 km
Flights per week 44
Departure airport Airport Panama City-Tocumen International (PTY)
Departure country Flights from Panama
Arrival airport Airport Santiago de Chile - Arturo Merino Benitez (SCL)
Destination country Flights to Chile
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