Flights from Panama City to Santiago de Chile

Our cheapest offers for flights from Panama City to Santiago de Chile

Here you can compare cheap flights from Panama City (PTY) to Santiago de Chile (SCL) for one-way or return trips. The following offers were searched for and found on idealo during the last few days. Or start your own flight search to Santiago de Chile. Prices and availability may change at any time.

Outbound Return Airlines Shop Baggage Price
Panama City
Santiago de Chile
Outbound
12/18/25
1 Stopover (BOG)
AV0057, AV0115
14h 25min
Return
01/08/26
1 Stopover (BOG)
AV0098, AV0040
20h 05min
Avianca
$669
Best option
Panama City
Santiago de Chile
Outbound
12/18/25
direct
CM0474
06h 32min
Return
01/08/26
direct
CM0118
06h 36min
Copa Airlines ?
$743
Panama City
Santiago de Chile
Outbound
12/18/25
1 Stopover (IAH)
UA1031, UA0847
19h 15min
Return
01/08/26
1 Stopover (IAH)
UA0846, UA1250
20h 22min
United Airlines
$2,835
Panama City
Santiago de Chile
Outbound
12/18/25
1 Stopover (BOG)
AV0057, AV0115
14h 25min
Return
01/08/26
1 Stopover (BOG)
AV0116, AV0040
11h 35min
Avianca ?
$723
Panama City
Santiago de Chile
Outbound
12/18/25
direct
CM0395
06h 33min
Return
01/08/26
direct
CM0498
06h 43min
Copa Airlines ?
$844
Panama City
Santiago de Chile
Outbound
12/18/25
2 Stopovers (MEX, BOG)
AM0465, AM0717, JA0791
36h 23min
Return
01/08/26
2 Stopovers (LIM, MIA)
H20802, H85590, AA0331
35h 40min
Aeroméxico, JetSmart ?
$1,437
Panama City
Santiago de Chile
Outbound
12/18/25
1 Stopover (BOG)
AV0057, AV0115
14h 25min
Return
01/08/26
1 Stopover (BOG)
AV0116, AV0056
31h 35min
Avianca ?
$1,926
Prices based on recent searches, subject to last-minute changes
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Tips and tricks to help you find cheap flights from Panama City to Santiago de Chile

Favorite airline: Avianca
100 % of travelers choose to book flights on this route with Avianca and Copa.
Avianca
70 %
Copa
30 %
Stopover flights are the cheapest connection
Flights with a stopover are on average $290.00 cheaper than direct flights.
non stop flight
1 stop
06h 36min
14h 45min
642 US$
352 US$
Favourite connection: via Bogota
70 % of booked tickets on this route are for flights with a transfer in Bogota.
Route
bookings
1 stopover Bogota
14h 45min, from 352 US$
70 %
Direct flights
06h 36min, from 642 US$
30 %

Important flight information

Flight information: Panama City - Santiago de Chile

Roundtrip from 668,40 US$
Flight duration min. 06:26 / max. 06:39
Return flight duration min. 06:46/ max. 07:00
Distance 4814 km
Flights per week 44
Departure airport Airport Panama City-Tocumen International (PTY)
Departure country Flights from Panama
Arrival airport Airport Santiago de Chile - Arturo Merino Benitez (SCL)
Destination country Flights to Chile