- Fastest outbound flight
- Fastest inbound flight
- non-stop flights
- 9x / week
- Flight distance
- 8,166 km
- Time difference
- Most popular airlines
- Air Europa Lineas Aereas
- Iberia
- Air Europa Lineas Aereas
Flight schedule from Panama City (PTY) to Madrid (MAD)
Select a travel date in the flight schedule for the route from Panama City (PTY) to Madrid (MAD) and compare affordable flight deals.
offers
Active filtersnone
Matching outbound flights7 of 7
fromto
dep.arr.
durationstopovers
- September 20 – 26, 2026
- Sep 27 – Oct 3, 2026
- October 4 – 10, 2026
- PTYMAD1 stopover
- PTYMAD1 stopover
- PTYMAD1 stopover
- PTYMAD1 stopover
- PTYMADnonstop
- PTYMADnonstop
- PTYMAD1 stopover
Tips and tricks to help you find cheap flights from Panama City to Madrid
Favorite airline: Air Europa
The favorite airline for flights from Panama City to Madrid is Air Europa.
Air Europa
48 %
Iberia
39 %
Avianca
9 %
Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Panama City to Madrid?
A nonstop flight from Panama City to Madrid typically takes around 9 hours 35 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 14 hours 20 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.
Are there nonstop flights from Panama City to Madrid?
Yes, there are nonstop flights from Panama City to Madrid, although not necessarily every day. On average, around 9 to 10 flights per week are available. If you have flexibility with your travel dates, you will have an easier time finding a suitable nonstop connection.
Which airlines fly from Panama City to Madrid?
Direct flights from Panama City to Madrid are operated by, among others, Air Europa and Iberia. Connecting flights with one stop are also available, for example with Avianca (via Bogota), Air France (via Paris - Charles de Gaulle) and Turkish Airlines (via Istanbul). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.
On which days are there nonstop flights from Panama City to Madrid?
Nonstop flights from Panama City to Madrid operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Panama City to Madrid?
On the route from Panama City to Madrid, there are on average around 1 to 2 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.
How many flights per week are there from Panama City to Madrid?
On the route from Panama City to Madrid, there are around 9 to 10 flights per week. The number of flights can vary depending on the season and day of the week. If you have flexibility, it is worth looking at several departure days.
When does the first flight from Panama City to Madrid depart?
The earliest nonstop flight from Panama City to Madrid usually departs at 6:35 PM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Madrid.
When does the last flight from Panama City to Madrid depart?
The last nonstop flight from Panama City to Madrid usually departs at 10:35 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.