Question 1

How long is the flight from Panama City to Madrid?

Accepted Answer

A nonstop flight from Panama City to Madrid typically takes around 10 hours 50 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 17 hours 15 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.

Question 2

Are there nonstop flights from Panama City to Madrid?

Accepted Answer

Yes, there are nonstop flights from Panama City to Madrid, although not necessarily every day. On average, around 11 to 12 flights per week are available. If you have flexibility with your travel dates, you will have an easier time finding a suitable nonstop connection.

Question 3

Which airlines fly from Panama City to Madrid?

Accepted Answer

Direct flights from Panama City to Madrid are operated by, among others, Air Europa and Iberia. Connecting flights with one stop are also available, for example with Avianca (via Bogota), United Airlines (via Newark) and Aeroméxico (via Mexico City). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.

Question 4

On which days are there nonstop flights from Panama City to Madrid?

Accepted Answer

Nonstop flights from Panama City to Madrid operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.

Question 5

How many flights are there per day from Panama City to Madrid?

Accepted Answer

On the route from Panama City to Madrid, there are on average around 1 to 2 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.

Question 6

How many flights per week are there from Panama City to Madrid?

Accepted Answer

On the route from Panama City to Madrid, there are around 11 to 12 flights per week. The number of flights can vary depending on the season and day of the week. If you have flexibility, it is worth looking at several departure days.

Question 7

When does the first flight from Panama City to Madrid depart?

Accepted Answer

The earliest nonstop flight from Panama City to Madrid usually departs at 5:35 PM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Madrid.

Question 8

When does the last flight from Panama City to Madrid depart?

Accepted Answer

The last nonstop flight from Panama City to Madrid usually departs at 10:35 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.

	Outbound	Return	Airlines	Baggage	Price
Best option Panama City Madrid	Outbound 06/25/26 direct UX0056 09h 50min	Return 06/30/26 direct UX0055 10h 35min	Air Europa Lineas Aereas		$983
Panama City Madrid Please note: transfer for connecting flight	Outbound 08/20/26 1 Stopover (MIA) CM0334, IB0334 14h 20min	Return 08/25/26 1 Stopover (SJO) E90857, CM0461 23h 13min	Copa Airlines, Iberia		$1,469
Panama City Madrid	Outbound 06/25/26 direct UX0056 09h 50min	Return 06/30/26 direct UX0055 10h 35min	Air Europa Lineas Aereas		$987
Panama City Madrid	Outbound 06/25/26 direct UX0056 09h 50min	Return 06/30/26 direct UX0055 10h 35min	Air Europa Lineas Aereas		$989
Panama City Madrid	Outbound 06/25/26 direct UX0056 09h 50min	Return 06/30/26 direct UX0055 10h 35min	Air Europa Lineas Aereas		$999
Panama City Madrid	Outbound 06/25/26 direct UX0056 09h 50min	Return 06/30/26 direct UX0055 10h 35min	Air Europa Lineas Aereas		$1,023
Panama City Madrid	Outbound 06/25/26 direct UX0056 09h 50min	Return 06/30/26 direct UX0055 10h 35min	Air Europa Lineas Aereas	?	$1,050
Panama City Madrid	Outbound 06/25/26 direct UX0056 09h 50min	Return 06/30/26 direct UX0055 10h 35min	Air Europa Lineas Aereas	?	$1,116
Panama City Madrid	Outbound 08/20/26 1 Stopover (MIA) AA2964, AA8741 35h 06min	Return 08/25/26 1 Stopover (MIA) AA8645, AA0959 27h 14min	American Airlines	?	$1,123
Panama City Madrid	Outbound 08/20/26 1 Stopover (MIA) IB4369, IB0338 16h 11min	Return 08/25/26 1 Stopover (SJO) IB0243, IB7769 16h 12min	Iberia	?	$1,220

Roundtrip from	$982.50
Flight duration	min. 10:05
Return flight duration	min. 10:55
Distance	8166 km
Flights per week	8
Departure airport	Airport Panama City-Tocumen International (PTY)
Departure country	Flights from Panama
Arrival airport	Airport Madrid-Barajas (MAD)
Destination country	Flights to Spain
Departure country - Arrival airport	Panama - Madrid-Barajas
Departure airport - Destination country	Panama City-Tocumen International - Spain

Flight Routes from Panama City to Madrid

Our cheapest offers for flights from Panama City to Madrid

Panama City-Tocumen International

Madrid-Barajas

Tips and tricks to help you find cheap flights from Panama City to Madrid

Important flight information

Frequently Asked Questions (FAQ)

Flight information: Panama City - Madrid

Flight destinations with a similar price

Flight destinations with a similar price