Flights from Panama City to Madrid

Our cheapest offers for flights from Panama City to Madrid

Here you can compare cheap flights from Panama City (PTY) to Madrid (MAD) for one-way or return trips. The following offers were searched for and found on idealo during the last few days. Or start your own flight search to Madrid. Prices and availability may change at any time.

Outbound Return Airlines Shop Baggage Price
Panama City
Madrid
Outbound
01/06/26
1 Stopover (BOG)
AV0041, AV0046
14h 25min
Return
01/18/26
2 Stopovers (LIS, MIA)
TP1023, TP0223, CM0227
18h 57min
Avianca ?
$1,411
Offers unavailable
Best option
Panama City
Madrid
Outbound
01/06/26
direct
UX0056
09h 35min
Return
01/18/26
direct
UX0055
10h 35min
Air Europa Lineas Aereas
$1,441
Panama City
Madrid
Please note: transfer for connecting flight
Outbound
01/06/26
1 Stopover (BOG)
AV0041, AV0046
14h 25min
Return
01/18/26
1 Stopover (BOG)
IB0153, AV0040
14h 30min
Avianca
$2,433
Offers unavailable
Panama City
Madrid
Outbound
01/06/26
direct
UX0056
09h 35min
Return
01/18/26
direct
UX0055
10h 35min
Air Europa Lineas Aereas
$1,442
Panama City
Madrid
Outbound
01/06/26
direct
UX0056
09h 35min
Return
01/18/26
direct
UX0055
10h 35min
Air Europa Lineas Aereas
$1,464
Panama City
Madrid
Outbound
01/06/26
direct
UX0056
09h 35min
Return
01/18/26
direct
UX0055
10h 35min
Air Europa Lineas Aereas ?
$1,478
Panama City
Madrid
Outbound
01/06/26
direct
UX0056
09h 35min
Return
01/18/26
direct
UX0055
10h 35min
Air Europa Lineas Aereas ?
$1,518
Panama City
Madrid
Outbound
01/06/26
1 Stopover (BOG)
AV0041, AV0046
14h 25min
Return
01/18/26
1 Stopover (HAV)
IB0273, IB7733
25h 30min
Avianca ?
$1,552
Offers unavailable
Panama City
Madrid
Outbound
01/06/26
direct
UX0056
09h 35min
Return
01/18/26
direct
UX0055
10h 35min
Air Europa Lineas Aereas ?
$1,588
Panama City
Madrid
Outbound
01/06/26
2 Stopovers (MIA, LHR)
IB4826, IB3585, IB3649
18h 24min
Return
01/18/26
1 Stopover (MIA)
IB0337, IB4341
27h 02min
Iberia ?
$1,768
Prices based on recent searches, subject to last-minute changes
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Tips and tricks to help you find cheap flights from Panama City to Madrid

Favorite airline: Air Europa
The favorite airline for flights from Panama City to Madrid is Air Europa.
Air Europa
48 %
Iberia
39 %
Avianca
9 %
Direct flights are the cheapest connection
Compared to flights with a stopover, direct flights are $336.00 cheaper on this route.
non stop flight
1 stop
2 stops
09h 50min
19h 05min
27h 35min
$610
$946
$1,730
The favorite connection is non-stop
Non-stop flights are especially popular on this route. 86 % of travelers will book a direct flight.
Route
bookings
Direct flights
09h 50min, from $610
86 %
1 stopover Bogota
19h 05min, from $946
9 %
2 stopovers Miami International Airport, FL Frankfurt-Main
27h 35min, from $1,730
5 %

Important flight information

Flight information: Panama City - Madrid

Roundtrip from $1,410.90
Flight duration min. 10:05
Return flight duration min. 10:55
Distance 8166 km
Flights per week 8
Departure airport Airport Panama City-Tocumen International (PTY)
Departure country Flights from Panama
Arrival airport Airport Madrid-Barajas (MAD)
Destination country Flights to Spain
Flight destinations with a similar price