- Fastest flight
- non-stop flights
- 3x / week
- Flight distance
- 4,431 km
- Time difference
- Most popular airlines
- JetSmart
- Jet Ops
- JetSmart
Flight schedule from Medellin (MDE) to Santiago de Chile (SCL)
Select a travel date in the flight schedule for the route from Medellin (MDE) to Santiago de Chile (SCL) and compare affordable flight deals.
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Matching outbound flightsMDE–SCL · 3 of 3
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- Sep 27 – Oct 3, 2026
- October 4 – 10, 2026
- October 11 – 17, 2026
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- MDESCL1 stopover
- MDESCL1 stopover
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Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Medellin to Santiago de Chile?
A nonstop flight from Medellin to Santiago de Chile typically takes around 6 hours 12 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 9 hours. For the quickest trip, a nonstop flight is usually the most comfortable choice.
Are there nonstop flights from Medellin to Santiago de Chile?
Yes, there are nonstop flights from Medellin to Santiago de Chile, although not necessarily every day. On average, around 3 to 4 flights per week are available. If you have flexibility with your travel dates, you will have an easier time finding a suitable nonstop connection.
Which airlines fly from Medellin to Santiago de Chile?
Direct flights from Medellin to Santiago de Chile are operated by, among others, JetSmart and Jet Ops. Connecting flights with one stop are also available, for example with Avianca (via Bogota), Copa (via Panama City) and JetSmart (via Lima). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.
On which days are there nonstop flights from Medellin to Santiago de Chile?
Nonstop flights from Medellin to Santiago de Chile operate Monday, Thursday, Friday and Sunday. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Medellin to Santiago de Chile?
On the route from Medellin to Santiago de Chile, there is less than one flight per day on average. The exact number can vary by day of the week and season. If you have flexibility with your travel dates, it is worth comparing several departure days.
How many flights per week are there from Medellin to Santiago de Chile?
On the route from Medellin to Santiago de Chile, there are around 3 to 4 flights per week. The number of flights can vary depending on the season and day of the week. If you have flexibility, it is worth looking at several departure days.
When does the first flight from Medellin to Santiago de Chile depart?
The earliest nonstop flight from Medellin to Santiago de Chile usually departs at 5:01 PM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Santiago de Chile.
When does the last flight from Medellin to Santiago de Chile depart?
The last nonstop flight from Medellin to Santiago de Chile usually departs at 5:01 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.