Flights from Madrid to Santiago de Chile

Our cheapest offers for flights from Madrid to Santiago de Chile

Here you can compare cheap flights from Madrid (MAD) to Santiago de Chile (SCL) for one-way or return trips. The following offers were searched for and found on idealo during the last few days. Or start your own flight search to Santiago de Chile. Prices and availability may change at any time.

Outbound Return Airlines Shop Baggage Price
Madrid
Santiago de Chile
Outbound
12/08/25
1 Stopover (GRU)
LA1525, LA8017
17h 45min
Return
12/22/25
1 Stopover (PUJ)
X11693, X14286
24h 05min
LATAM Chile
$1,294
found 3 days ago
Best option
Madrid
Santiago de Chile
Outbound
12/08/25
direct
IB0113
13h 20min
Return
12/22/25
direct
IB0118
12h 35min
Iberia ?
$1,422
found 3 days ago
Madrid
Santiago de Chile
Outbound
12/08/25
2 Stopovers (LIS, GIG)
TP1011, TP0073, H20621
32h 55min
Return
12/22/25
2 Stopovers (GIG, LIS)
H20620, TP0074, TP1010
24h 30min
TAP Air Portugal, Sky Airline
$1,977
found 3 days ago
Madrid
Santiago de Chile
Please note: transfer for connecting flight
Outbound
12/08/25
direct
IB6651
13h 25min
Return
12/22/25
1 Stopover (GRU)
LA0630, IB0272
16h 40min
Iberia
$2,041
found 3 days ago
Madrid
Santiago de Chile
Outbound
12/08/25
3 Stopovers (LIS, IAD, BWI, IAH)
TP1011, TP0231, UA1898, UA0847
74h 30min
Return
12/22/25
2 Stopovers (PTY, SDQ)
CM0396, CM0107, UX0186
46h 23min
TAP Air Portugal, United Airlines ?
$1,325
found 3 days ago
Madrid
Santiago de Chile
Outbound
12/08/25
direct
LA0707
13h 25min
Return
12/22/25
1 Stopover (LIM)
LA0520, LA2484
21h 28min
LATAM Chile ?
$1,389
found 3 days ago
Madrid
Santiago de Chile
Outbound
12/08/25
1 Stopover (GRU)
LA1525, LA8017
17h 45min
Return
12/22/25
1 Stopover (BOG)
AV0098, AV0010
26h 00min
LATAM Chile ?
$1,438
found 3 days ago
Madrid
Santiago de Chile
Outbound
12/08/25
1 Stopover (GRU)
LA1525, LA8017
17h 45min
Return
12/22/25
1 Stopover (EZE)
LA0542, UX0042
17h 55min
LATAM Chile ?
$1,490
found 3 days ago
Madrid
Santiago de Chile
Outbound
12/08/25
1 Stopover (GRU)
LA1525, LA8017
17h 45min
Return
12/22/25
direct
LA5413
12h 40min
LATAM Chile ?
$2,665
found 3 days ago
Prices based on recent searches, subject to last-minute changes
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Tips and tricks to help you find cheap flights from Madrid to Santiago de Chile

Favorite airline: Iberia
85 % of flights booked on the route from Madrid to Santiago de Chile are booked with Iberia, Avianca and Delta.
Iberia
46 %
Avianca
31 %
Delta
8 %
Direct flights are more expensive
Compared to flights with a stopover, direct flights are $117.00 more expensive on this route.
non stop flight
1 stop
2 stops
13h 31min
25h 35min
27h 00min
$898
$781
$883
The favorite connection is non-stop
Non-stop flights are especially popular on this route. 50 % of travelers will book a direct flight.
Route
bookings
Direct flights
13h 31min, from $898
50 %
1 stopover Bogota
25h 35min, from $781
40 %
2 stopovers New York - John F. Kennedy International Airport, NY Hartsfield-Jackson Atlanta International Airport, GA
27h 00min, from $883
10 %

Important flight information

Flight information: Madrid - Santiago de Chile

Roundtrip from $1,293.40
Flight duration min. 13:30 / max. 13:40
Return flight duration min. 12:50
Distance 10732 km
Flights per week 19
Departure airport Airport Madrid-Barajas (MAD)
Departure country Flights from Spain
Arrival airport Airport Santiago de Chile - Arturo Merino Benitez (SCL)
Destination country Flights to Chile
Flight destinations with a similar price