Question 1

How long is the flight from Madrid to Santa Cruz?

Accepted Answer

A nonstop flight from Madrid to Santa Cruz typically takes around 10 hours 15 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 20 hours 45 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.

Question 2

Are there nonstop flights from Madrid to Santa Cruz?

Accepted Answer

Yes, there are nonstop flights from Madrid to Santa Cruz, although not necessarily every day. On average, around 2 to 3 flights per week are available. If you have flexibility with your travel dates, you will have an easier time finding a suitable nonstop connection.

Question 3

Which airlines fly from Madrid to Santa Cruz?

Accepted Answer

Direct flights from Madrid to Santa Cruz are operated by, among others, Air Europa. Connecting flights with one stop are also available, for example with Avianca (via Bogota) and LATAM Chile (via Lima). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.

Question 4

On which days are there nonstop flights from Madrid to Santa Cruz?

Accepted Answer

Nonstop flights from Madrid to Santa Cruz operate Monday, Wednesday, Saturday and Sunday. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.

Question 5

How many flights are there per day from Madrid to Santa Cruz?

Accepted Answer

On the route from Madrid to Santa Cruz, there is less than one flight per day on average. The exact number can vary by day of the week and season. If you have flexibility with your travel dates, it is worth comparing several departure days.

Question 6

How many flights per week are there from Madrid to Santa Cruz?

Accepted Answer

On the route from Madrid to Santa Cruz, there are only a few flights per week. It is therefore especially worthwhile to be flexible with your travel dates so you can more easily find a suitable departure day.

Question 7

When does the first flight from Madrid to Santa Cruz depart?

Accepted Answer

The earliest nonstop flight from Madrid to Santa Cruz usually departs at 3:05 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Santa Cruz.

Question 8

When does the last flight from Madrid to Santa Cruz depart?

Accepted Answer

The last nonstop flight from Madrid to Santa Cruz usually departs at 11:35 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.

	Outbound	Return	Airlines	Baggage	Price
Madrid Santa Cruz	Outbound 08/20/26 1 Stopover (EZE, AEP) AR1133, AR1368 35h 05min	Return 08/25/26 1 Stopover (AEP, EZE) AR1369, AR1132 32h 50min	Aerolineas Argentinas		$1,403
Best option Madrid Santa Cruz	Outbound 08/20/26 1 Stopover (BOG) AV0027, AV0167 24h 20min	Return 08/25/26 1 Stopover (BOG) AV0166, AV0046 14h 45min	Avianca	?	$1,671
Madrid Santa Cruz Please note: transfer for connecting flight	Outbound 08/20/26 1 Stopover (VCP, GRU) AD8755, G37638 27h 20min	Return 08/25/26 1 Stopover (GRU) OB0736, IB0272 19h 40min	Azul Brazilian Airlines, Gol Transportes Aéreos		$1,953
Madrid Santa Cruz	Outbound 08/20/26 1 Stopover (EZE, AEP) AR1133, AR1368 35h 05min	Return 08/25/26 1 Stopover (AEP, EZE) AR1369, AR1132 32h 50min	Aerolineas Argentinas		$1,410
Madrid Santa Cruz	Outbound 08/20/26 1 Stopover (EZE, AEP) AR1133, AR1368 35h 05min	Return 08/25/26 1 Stopover (AEP, EZE) AR1369, AR1132 32h 50min	Aerolineas Argentinas	?	$1,434
Madrid Santa Cruz	Outbound 08/20/26 2 Stopovers (CDG, GRU) AF1101, AF0454, OB0739 30h 10min	Return 08/25/26 2 Stopovers (PTY, AMS) CM0220, KL0758, KL1509 29h 38min	Air France, Boliviana de Aviacion		$1,521
Madrid Santa Cruz	Outbound 08/20/26 1 Stopover (LIM) PU0301, OB0741 23h 30min	Return 08/25/26 1 Stopover (EZE) OB0700, PU0502 26h 35min	Plus Ultra Líneas Aéreas, Boliviana de Aviacion		$1,681
Madrid Santa Cruz	Outbound 08/20/26 1 Stopover (BOG) AV0183, AV0167 21h 25min	Return 08/25/26 1 Stopover (BOG) AV0166, AV0046 14h 45min	Avianca	?	$1,706
Madrid Santa Cruz	Outbound 08/20/26 2 Stopovers (BCN, MAD) IB0403, IB0414, IB7790 42h 40min	Return 08/25/26 4 Stopovers (PTY, IAD, DCA, EWR, JFK, DUB) UA7189, UA7066, UA4430, EI0104, EI0592 40h 08min	Iberia	?	$1,728
Madrid Santa Cruz	Outbound 08/20/26 1 Stopover (BOG) AV0183, AV0167 21h 25min	Return 08/25/26 1 Stopover (BOG) AV0166, AV0010 28h 30min	Avianca		$2,204

Roundtrip from	$ 1.402,19
Flight duration	min. 11:30 / max. 11:45
Return flight duration	min. 11:05/ max. 11:30
Distance	8928 km
Flights per week	9
Departure airport	Airport Madrid-Barajas (MAD)
Departure country	Flights from Spain
Arrival airport	Airport Santa Cruz Viru Viru International (VVI)
Destination country	Flights to Bolivia
Departure country - Arrival airport	Spain - Santa Cruz Viru Viru International
Departure airport - Destination country	Madrid-Barajas - Bolivia

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