Flight Routes from Frankfurt to Santa Cruz

Compare cheap outbound and return flights from Frankfurt (FRA) to Santa Cruz (VVI) and find the best offer from numerous airlines and travel agencies.

Trip type
Fastest flight
Flight distance
10,273 km
Time difference

Flight schedule from Frankfurt (FRA) to Santa Cruz (VVI)

Select a travel date in the flight schedule for the route from Frankfurt (FRA) to Santa Cruz (VVI) and compare affordable flight deals.

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Matching outbound flightsFRA–VVI · 4 of 4
fromto
dep.arr.
durationstopovers
  1. September 20 – 26, 2026
  2. Sep 27 – Oct 3, 2026
  3. October 4 – 10, 2026
    1. FRAVVI
      1 stopover
      1. Lufthansa
      2. Boliviana de Aviacion
    2. FRAVVI
      1 stopover
      1. Lufthansa
      2. Gol Transportes Aéreos
    3. FRAVVI
      1 stopover
      1. Lufthansa
      2. Gol Transportes Aéreos
    4. FRAVVI
      1 stopover
      1. Lufthansa
      2. Boliviana de Aviacion

      Tips and tricks to help you find cheap flights from Frankfurt to Santa Cruz

      Favorite airline: LATAM Chile
      64 % of flights from Frankfurt to Santa Cruz are booked with LATAM Chile.
      LATAM Chile
      64 %
      Lufthansa
      15 %
      Iberia
      12 %
      Favourite connection: via Sao Paulo
      Stopover flights on this route are especially popular via Sao Paulo, making up 66 % of bookings.
      Route
      bookings
      1 stopover Sao Paulo Guarulhos International Airport
      24h 10min, from 878 US$
      66 %
      2 stopovers Madrid-Barajas Sao Paulo Guarulhos International Airport
      39h 20min, from 937 US$
      14 %
      2 stopovers Madrid-Barajas Lima
      46h 00min, from 883 US$
      10 %

      Important flight information

      Frequently Asked Questions (FAQ)

      How long is the flight from Frankfurt to Santa Cruz?
      The route from Frankfurt to Santa Cruz is served by connecting flights with one stop. These typically take around 17 hours 40 minutes, depending on the layover time and the connection chosen. If travel time matters to you, look especially for connections with a short layover.
      Are there nonstop flights from Frankfurt to Santa Cruz?
      No, there are currently no nonstop flights from Frankfurt to Santa Cruz. However, you can reach Santa Cruz with a one-stop connecting flight. Allow extra travel time for the connection and pay close attention to the length of the layover.
      Which airlines fly from Frankfurt to Santa Cruz?
      Flights from Frankfurt to Santa Cruz are available with one stop, operated by, among others, Air Europa (via Madrid). When comparing options, look beyond the fare and consider the total travel time and the length of the layover.

      Discover more flights around Frankfurt and Santa Cruz

      Departure airport Airport Frankfurt-Main (FRA)
      Departure country Flights from Germany
      Arrival airport Airport Santa Cruz Viru Viru International (VVI)
      Destination country Flights to Bolivia
      Departure country - Arrival airport Germany - Santa Cruz Viru Viru International
      Departure airport - Destination country Frankfurt-Main - Bolivia