- Fastest flight
- non-stop flights
- 33x / week
- Flight distance
- 708 km
- Time difference
- Most popular airlines
- Delta Air Lines
- Southwest Airlines
- Delta Air Lines
Flight schedule from Detroit (DTW) to St. Louis (STL)
Select a travel date in the flight schedule for the route from Detroit (DTW) to St. Louis (STL) and compare affordable flight deals.
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Matching outbound flights12 of 12
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- September 13 – 19, 2026
- September 20 – 26, 2026
- Sep 27 – Oct 3, 2026
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- DTWSTLnonstop
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- DTWSTLnonstop
- DTWSTLnonstop
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Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Detroit to St. Louis?
A nonstop flight from Detroit to St. Louis typically takes around 1 hour 40 minutes. This makes the nonstop service the fastest and most convenient way to travel between Detroit and St. Louis. It is worth checking flight times when searching, as they can vary by airline and travel date.
Are there nonstop flights from Detroit to St. Louis?
Yes, there are nonstop flights from Detroit to St. Louis, averaging around 4 to 5 flights per day, operated by, among others, Delta and Southwest. If you want to fly without a layover, it is worth filtering specifically for nonstop flights when searching.
Which airlines fly from Detroit to St. Louis?
Direct flights from Detroit to St. Louis are operated by, among others, Delta and Southwest. These flights take you to St. Louis nonstop, making them especially practical for short trips or weekend getaways. It is still worth comparing departure times and airline policies, as baggage rules and fees can vary.
On which days are there nonstop flights from Detroit to St. Louis?
Nonstop flights from Detroit to St. Louis operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Detroit to St. Louis?
On the route from Detroit to St. Louis, there are on average around 4 to 5 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.
How many flights per week are there from Detroit to St. Louis?
From Detroit to St. Louis, there are around 33 to 34 flights per week. This means you usually have connections available on several days and at various times. Beyond the price, it is worth comparing flight duration, airline, and any potential additional fees.
When does the first flight from Detroit to St. Louis depart?
The earliest nonstop flight from Detroit to St. Louis usually departs at 6:10 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in St. Louis.
When does the last flight from Detroit to St. Louis depart?
The last nonstop flight from Detroit to St. Louis usually departs at 9:20 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.