- Cheapest roundtrip flight
- from€308
- Fastest flight
- non-stop flights
- 44x / week
- Flight distance
- 1,569 km
- Time difference
- Most popular airlines
- Southwest Airlines

- United Airlines

- Frontier Airlines

- Southwest Airlines
Flight schedule from Denver (DEN) to Indianapolis (IND)
Select a travel date in the flight schedule for the route from Denver (DEN) to Indianapolis (IND) and compare affordable flight deals.
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Matching outbound flightsDEN–IND · 25 of 25
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- October 11 – 17, 2026
- October 18 – 24, 2026
- October 25 – 31, 2026
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Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Denver to Indianapolis?
A nonstop flight from Denver to Indianapolis typically takes around 2 hours 20 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 6 hours 45 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.
Are there nonstop flights from Denver to Indianapolis?
Yes, there are nonstop flights from Denver to Indianapolis, averaging around 6 to 7 flights per day, operated by, among others, Southwest, United Airlines and Frontier Airlines. If you want to fly without a layover, it is worth filtering specifically for nonstop flights when searching.
Which airlines fly from Denver to Indianapolis?
Direct flights from Denver to Indianapolis are operated by, among others, Southwest, United Airlines and Frontier Airlines. Connecting flights with one stop are also available, for example with Delta (via Minneapolis). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.
On which days are there nonstop flights from Denver to Indianapolis?
Nonstop flights from Denver to Indianapolis operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Denver to Indianapolis?
From Denver to Indianapolis, there are on average around 6 to 7 flights per day. This usually means you have a good choice of departure times. If you are flexible, you can easily compare times, prices, and airlines.
How many flights per week are there from Denver to Indianapolis?
From Denver to Indianapolis, there are around 44 to 45 flights per week. This means you usually have connections available on several days and at various times. Beyond the price, it is worth comparing flight duration, airline, and any potential additional fees.
When does the first flight from Denver to Indianapolis depart?
The earliest nonstop flight from Denver to Indianapolis usually departs at 5:05 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Indianapolis.
When does the last flight from Denver to Indianapolis depart?
The last nonstop flight from Denver to Indianapolis usually departs at 9:15 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.