| Outbound | Return | Airlines | Shop | Baggage | Price | ||
|---|---|---|---|---|---|---|---|
| Chicago St. Louis | Outbound 02/14/26 2 Stopovers (IAH, ATL) F93135, F91404, F94473 46h 46min | Return - |  Frontier Airlines |  | ? | $160 | |
| Best option Chicago St. Louis | Outbound 03/28/26 direct AA3712 01h 23min | Return 04/25/26 direct AA2444 01h 27min |  American Airlines |  | ? | $183 | |
| Chicago St. Louis | Outbound 05/16/26 direct AA2956 01h 16min | Return 05/29/26 direct UA4411 01h 38min | American Airlines | | ? | $235 | |
| Chicago St. Louis | Outbound 03/28/26 direct AA3573 01h 25min | Return 04/25/26 direct AA4337 01h 29min | American Airlines |  | ? | $249 | |
| Chicago St. Louis | Outbound 05/16/26 direct UA4464 01h 26min | Return 05/29/26 direct UA0533 01h 31min |  United Airlines | | ? | $263 | |
| Chicago St. Louis | Outbound 03/28/26 direct AA3573 01h 25min | Return 04/25/26 direct AA4135 01h 30min | American Airlines |  | ? | $311 | |
| Chicago St. Louis | Outbound 03/28/26 1 Stopover (ATL) F92198, F94473 17h 40min | Return 04/25/26 1 Stopover (DEN) F94567, F93174 13h 38min | Frontier Airlines | | ? | $345 | |
| Chicago St. Louis | Outbound 05/16/26 direct AA1926 01h 22min | Return 05/29/26 direct AA2324 01h 30min | American Airlines | | ? | $347 | |
| Chicago St. Louis | Outbound 04/03/26 direct AA4532 01h 22min | Return 04/16/26 direct AA1926 01h 21min | American Airlines | | ? | $369 | |
| Chicago St. Louis | Outbound 04/03/26 direct UA2379 01h 28min | Return 04/16/26 direct UA4423 01h 29min | United Airlines | | ? | $386 |
Tips and tricks to help you find cheap flights from Chicago to St. Louis
Favorite airline: Southern Airways Express
52 % of flights from Chicago to St. Louis are booked with Southern Airways Express.
Southern Airways Express
52 %
United Airlines
22 %
Spirit Airlines
11 %