| Outbound | Return | Airlines | Shop | Baggage | Price | ||
|---|---|---|---|---|---|---|---|
| Best option Chicago St. Louis | Outbound 03/28/26 direct AA3712 01h 23min | Return 04/25/26 direct AA2444 01h 27min |  American Airlines |  | ? | $183 | |
| Chicago St. Louis | Outbound 07/26/26 direct AA4104 01h 26min | Return 08/05/26 direct AA1926 01h 24min | American Airlines | | ? | $210 | |
| Chicago St. Louis | Outbound 03/28/26 direct AA3573 01h 25min | Return 04/25/26 direct AA4337 01h 29min | American Airlines |  | ? | $249 | |
| Chicago St. Louis | Outbound 05/16/26 direct UA4464 01h 26min | Return 05/29/26 direct UA0533 01h 31min |  United Airlines | | ? | $263 | |
| Chicago St. Louis | Outbound 03/28/26 direct AA3573 01h 25min | Return 04/25/26 direct AA4135 01h 30min | American Airlines |  | ? | $311 | |
| Chicago St. Louis | Outbound 03/28/26 1 Stopover (ATL) F92198, F94473 17h 40min | Return 04/25/26 1 Stopover (DEN) F94567, F93174 13h 38min |  Frontier Airlines |  | ? | $345 | |
| Chicago St. Louis | Outbound 07/26/26 1 Stopover (DFW) F91341, F91524 12h 07min | Return 08/05/26 1 Stopover (ATL) F94474, F93397 06h 49min | Frontier Airlines |  | $438 | ||
| Chicago St. Louis | Outbound 07/26/26 1 Stopover (ATL) F91596, F94473 25h 17min | Return 08/05/26 2 Stopovers (DEN, MSP) F94567, SY0652, SY0261 23h 51min | Frontier Airlines | | ? | $456 | |
| Chicago St. Louis | Outbound 07/26/26 1 Stopover (ATL) F91596, F94473 06h 52min | Return 08/05/26 1 Stopover (PDX) AS1634, AS0376 10h 40min | Frontier Airlines |  | ? | $532 | |
| Chicago St. Louis | Outbound 05/16/26 1 Stopover (SEA) AS0715, AS0618 09h 50min | Return 05/29/26 1 Stopover (SEA) AS0314, AS0328 10h 44min |  Alaska Airlines | | ? | $618 |
Tips and tricks to help you find cheap flights from Chicago to St. Louis
Favorite airline: Southern Airways Express
52 % of flights from Chicago to St. Louis are booked with Southern Airways Express.
Southern Airways Express
52 %
United Airlines
22 %
Spirit Airlines
11 %