Flight Routes from Charleston to St. Louis

Compare cheap outbound and return flights from Charleston (CHS) to St. Louis (STL) and find the best offer from numerous airlines and travel agencies.

Cheapest roundtrip flight: from€412
Fastest flight: 2h 50min
non-stop flights: 6x / week
Flight distance: 1,136 km
Time difference: -1 hour

Cheap flight offers from Charleston-SC to St. Louis

sorted by price and recency

Thu, Dec 31, 2026 – Fri, Jan 29, 2027
20:02 – 23:58
CHS–STL
4h 56min
1 stopover
08:13 – 13:23
STL–CHS
4h 10min
1 stopover
€3,194
Thu, Dec 31, 2026 – Sun, Jan 31, 2027
08:30 – 16:50
CHS–STL
57h 20min
4 stopovers
17:20 – 17:19
STL–CHS
46h 59min
3 stopovers
€2,915
Thu, Dec 31, 2026 – Sat, Jan 30, 2027
06:31 – 13:19
CHS–STL
7h 48min
2 stopovers
17:37 – 00:26
STL–CHS
5h 49min
1 stopover
€578
Thu, Dec 31, 2026 – Fri, Jan 29, 2027
10:57 – 16:06
CHS–STL
6h 9min
1 stopover
08:13 – 14:59
STL–CHS
5h 46min
1 stopover
€416
Thu, Dec 31, 2026 – Fri, Jan 29, 2027
16:55 – 23:38
CHS–STL
7h 43min
1 stopover
06:30 – 14:06
STL–CHS
6h 36min
1 stopover
€412

Important flight information

Discover more flights around Charleston and St. Louis

Departure airport	Airport Charleston-SC (CHS)
Arrival airport	Airport St. Louis - Lambert International Airport (STL)
Destination country	Flights to United States
Departure airport - Destination country	Charleston-SC - United States

Alternative routes to United States

Flight Charleston - New York from 329 US$
Flight Charleston - San Francisco from 450 US$
Flight Charleston - Buffalo from 289 US$
Flight Charleston - Washington-DC from 261 US$
Flight Charleston - Miami from 373 US$
Flight Charleston - Orlando from 209 US$
Flight Charleston - Salt Lake City from 516 US$
Flight Charleston - Newark from 352 US$
Flight Charleston - Portland from 390 US$
Flight Charleston - Los Angeles from 377 US$

Alternative flights to St. Louis

Flight New York - St. Louis from 300 US$
Flight Atlanta - St. Louis from 265 US$
Flight Tampa - St. Louis from 431 US$
Flight Los Angeles - St. Louis from 371 US$
Flight Denver - St. Louis from 330 US$
Flight Orlando - St. Louis from 329 US$
Flight Salt Lake City - St. Louis from 454 US$
Flight Las Vegas - St. Louis from 371 US$
Flight Seattle-Tacoma - St. Louis from 351 US$
Flight Newark - St. Louis from 300 US$

Flight destinations with a similar price

Flight St. Louis - Los Cabos from 525 US$
Flight St. Louis - Puerto Vallarta from 428 US$
Flight St. Louis - San Juan (Puerto Rico) from 510 US$
Flight St. Louis - Punta Cana from 611 US$
Flight St. Louis - Hamburg from 1 617 US$
Flight St. Louis - Frankfurt from 782 US$
Flight St. Louis - Vancouver from 380 US$
Flight St. Louis - Calgary from 521 US$
Flight St. Louis - Montreal from 661 US$
Flight St. Louis - Cancun from 476 US$

Flight destinations with a similar price

Flight Charleston - San Francisco from 450 US$
Flight Charleston - Miami from 373 US$
Flight Charleston - Portland from 390 US$
Flight Charleston - Los Angeles from 377 US$
Flight Charleston - New York from 389 US$
Flight Charleston - Las Vegas from 392 US$
Flight Charleston - Boston from 434 US$
Flight Charleston - Reno from 450 US$
Flight Charleston - Detroit Metropolitan Area from 416 US$
Flight Charleston - Denver from 403 US$