- Boston (BOS) Rome-Fiumicino (FCO)
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1–2 non-stop flights per dayat least 6h 55minfrom $452 - Atlanta (ATL) Rome-Fiumicino (FCO)
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1–3 non-stop flights per dayat least 8h 5minfrom $451 - Newark (EWR) Rome-Fiumicino (FCO)
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1–2 non-stop flights per dayat least 7h 35minfrom $476 - New York (JFK) Rome-Fiumicino (FCO)
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5–10 non-stop flights per dayat least 7hfrom $328 - Philadelphia (PHL) Rome-Fiumicino (FCO)
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1–4 non-stop flights per dayat least 7h 10minfrom $532 - Los Angeles (LAX) Rome-Fiumicino (FCO)
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1–2 non-stop flights per dayat least 10h 40minfrom $322 - Miami (MIA) Rome-Fiumicino (FCO)
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1–2 non-stop flights per dayat least 8h 50minfrom $461 - San Francisco (SFO) Rome-Fiumicino (FCO)
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1–2 non-stop flights per dayat least 10h 50minfrom $458 - Baltimore (BWI) Rome-Fiumicino (FCO)
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only flights with stopoverat least 11h 5minfrom $557 - Orlando (MCO) Rome-Fiumicino (FCO)
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only flights with stopoverat least 12hfrom $480