- Fastest flight
- non-stop flights
- 9x / week
- Flight distance
- 1,501 km
- Time difference
- Most popular airlines
- AraJet
- Wingo
- AraJet
Flight schedule from Santo Domingo (SDQ) to Medellin (MDE)
Select a travel date in the flight schedule for the route from Santo Domingo (SDQ) to Medellin (MDE) and compare affordable flight deals.
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Matching outbound flightsSDQ–MDE · 11 of 11
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- Sep 27 – Oct 3, 2026
- October 4 – 10, 2026
- October 11 – 17, 2026
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Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Santo Domingo to Medellin?
A nonstop flight from Santo Domingo to Medellin typically takes around 2 hours 30 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 4 hours 45 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.
Are there nonstop flights from Santo Domingo to Medellin?
Yes, there are nonstop flights from Santo Domingo to Medellin, although not necessarily every day. On average, around 9 to 10 flights per week are available. If you have flexibility with your travel dates, you will have an easier time finding a suitable nonstop connection.
Which airlines fly from Santo Domingo to Medellin?
Direct flights from Santo Domingo to Medellin are operated by, among others, AraJet and Wingo. Connecting flights with one stop are also available, for example with Avianca (via Bogota) and Copa (via Panama City). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.
On which days are there nonstop flights from Santo Domingo to Medellin?
Nonstop flights from Santo Domingo to Medellin operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Santo Domingo to Medellin?
On the route from Santo Domingo to Medellin, there are on average around 1 to 2 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.
How many flights per week are there from Santo Domingo to Medellin?
On the route from Santo Domingo to Medellin, there are around 9 to 10 flights per week. The number of flights can vary depending on the season and day of the week. If you have flexibility, it is worth looking at several departure days.
When does the first flight from Santo Domingo to Medellin depart?
The earliest nonstop flight from Santo Domingo to Medellin usually departs at 7:43 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Medellin.
When does the last flight from Santo Domingo to Medellin depart?
The last nonstop flight from Santo Domingo to Medellin usually departs at 7:30 PM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.