- Fastest flight
- non-stop flights
- 9x / week
- Flight distance
- 3,470 km
- Time difference
- Most popular airlines
- Copa Airlines
- Copa Airlines
Flight schedule from Santa Cruz (VVI) to Panama City (PTY)
Select a travel date in the flight schedule for the route from Santa Cruz (VVI) to Panama City (PTY) and compare affordable flight deals.
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Matching outbound flightsVVI–PTY · 2 of 2
fromto
dep.arr.
durationstopovers
- October 18 – 24, 2026
- October 25 – 31, 2026
- November 1 – 7, 2026
- VVIPTYnonstop
- VVIPTYnonstop
Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Santa Cruz to Panama City?
A nonstop flight from Santa Cruz to Panama City typically takes around 4 hours 54 minutes. If you choose a connecting flight, allow more travel time. Typical one-stop itineraries take around 11 hours 20 minutes. For the quickest trip, a nonstop flight is usually the most comfortable choice.
Are there nonstop flights from Santa Cruz to Panama City?
Yes, there are nonstop flights from Santa Cruz to Panama City, although not necessarily every day. On average, around 9 to 10 flights per week are available. If you have flexibility with your travel dates, you will have an easier time finding a suitable nonstop connection.
Which airlines fly from Santa Cruz to Panama City?
Direct flights from Santa Cruz to Panama City are operated by, among others, Copa. Connecting flights with one stop are also available, for example with Avianca (via Bogota). If travel time matters to you, a direct flight is usually the most convenient option. Connecting flights often give you more choice of departure times and airlines.
On which days are there nonstop flights from Santa Cruz to Panama City?
Nonstop flights from Santa Cruz to Panama City operate daily. The schedule may vary by season, so it is worth comparing several travel dates. If your preferred day does not have a nonstop flight, nearby departure days or short connecting flights may be a good alternative.
How many flights are there per day from Santa Cruz to Panama City?
On the route from Santa Cruz to Panama City, there are on average around 1 to 2 flights per day. The number of flights can vary by day of the week and season. If you are flexible with your dates, it is worth comparing several departure days.
How many flights per week are there from Santa Cruz to Panama City?
On the route from Santa Cruz to Panama City, there are around 9 to 10 flights per week. The number of flights can vary depending on the season and day of the week. If you have flexibility, it is worth looking at several departure days.
When does the first flight from Santa Cruz to Panama City depart?
The earliest nonstop flight from Santa Cruz to Panama City usually departs at 1:08 AM. The exact departure time may vary by day of the week and airline. Early flights are especially useful if you want to make the most of your arrival day in Panama City.
When does the last flight from Santa Cruz to Panama City depart?
The last nonstop flight from Santa Cruz to Panama City usually departs at 11:55 AM. Late flights can be convenient if you want to travel after work or in the evening. Do check whether it is a nonstop flight, as a connecting itinerary could push the arrival time significantly later.