- Fastest flight
- Flight distance
- 2,975 km
- Time difference
Flight schedule from Santa Cruz (VVI) to Medellin (MDE)
Select a travel date in the flight schedule for the route from Santa Cruz (VVI) to Medellin (MDE) and compare affordable flight deals.
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Matching outbound flightsVVI–MDE · 1 of 1
fromto
dep.arr.
durationstopovers
- December 20 – 26, 2026
- 12/27/26 – 1/2/27
- January 3 – 9, 2027
No flights could be found for the active filters.
- VVIMDE1 stopover
Important flight information
Frequently Asked Questions (FAQ)
How long is the flight from Santa Cruz to Medellin?
The route from Santa Cruz to Medellin is served by connecting flights with one stop. These typically take around 9 hours 7 minutes, depending on the layover time and the connection chosen. If travel time matters to you, look especially for connections with a short layover.
Are there nonstop flights from Santa Cruz to Medellin?
No, there are currently no nonstop flights from Santa Cruz to Medellin. However, you can reach Medellin with a one-stop connecting flight. Allow extra travel time for the connection and pay close attention to the length of the layover.
Which airlines fly from Santa Cruz to Medellin?
Flights from Santa Cruz to Medellin are available with one stop, operated by, among others, Copa (via Panama City). When comparing options, look beyond the fare and consider the total travel time and the length of the layover.